Chen Jian-Ming, Li Dong-Dong, Chen Yi-Shan, Lian Bo, Wang Xiao-Peng, Guo Yu-Hong, Xu Xiao-Long, Huang Po, Chen Teng-Fei, Liu Yang, Liu Qing-Quan
Department of Intensive Medicine, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China; Department of Gastroenterology, The 81th Group Army Hospital of the Chinese People's Liberation Army, Zhangjiakou, China.
Department of Cardiology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Ann Palliat Med. 2021 Mar;10(3):2958-2970. doi: 10.21037/apm-20-831. Epub 2021 Mar 1.
The present study aimed to explore the effectiveness of electro-acupuncture (EA) in combination with a local anesthetic used in Western medicine in preventing the side effects of gastroscopy.
A sample group of 150 patients were divided into three groups based on treatment methods: an EA group, a dyclonine hydrochloride mucilage group, and a combined treatment group. In the EA group, EA stimulation was given at the Hegu, Neiguan, and Zusanli acupoints; in the dyclonine hydrochloride mucilage group, patients took 10 mL of dyclonine hydrochloride mucilage orally; in the combined treatment group, prevention of side effects was attempted by administration of both acupuncture and oral local anesthetic. The incidences of nausea, emesis, salivation, cough, restlessness, and breath holding during gastroscopy were observed and recorded for the three groups. Mean arterial pressure, heart rate, and oxygen saturation were recorded before the examination, and changes in these measures were recorded as the gastroscope passed through the pylorus and after the examination. The visual analogue scale (VAS) values of nausea and emesis, the rate of successful first-pass intubation, and the time of gastroscopy were also recorded. Statistical analysis was performed using R-3.5.3 software.
Incidences of side effects (e.g., nausea, emesis, salivation, restlessness, and breath holding) during the examination were lower in the combined treatment group than in the EA group and the dyclonine hydrochloride mucilage group (P<0.05 and P<0.01, respectively). Furthermore, the changes in heart rate and oxygen saturation when the gastroscope passed through the pylorus and after the examination were better in the combined treatment group than in the EA group and dyclonine hydrochloride mucilage group (P<0.01). The VAS values of nausea and emesis, the first-pass success rate, and examination duration were also better for the combined treatment group than for the other two groups (P<0.05 and P<0.01).
EA combined with local anesthesia with dyclonine hydrochloride mucilage can alleviate side effects during gastroscopy, reduce patient pain, and improve the efficiency of the procedure.
本研究旨在探讨电针（EA）联合西药局部麻醉药在预防胃镜检查副作用方面的有效性。
将150例患者样本按治疗方法分为三组：电针组、盐酸达克罗宁胶浆组和联合治疗组。电针组在合谷、内关和足三里穴位给予电针刺激；盐酸达克罗宁胶浆组患者口服10 mL盐酸达克罗宁胶浆；联合治疗组通过针刺和口服局部麻醉药联合使用来预防副作用。观察并记录三组患者在胃镜检查期间恶心、呕吐、流涎、咳嗽、躁动和屏气的发生率。在检查前记录平均动脉压、心率和血氧饱和度，并记录胃镜通过幽门时以及检查后的这些指标变化。还记录恶心和呕吐的视觉模拟量表（VAS）值、首次插管成功率和胃镜检查时间。使用R - 3.5.3软件进行统计分析。
联合治疗组检查期间副作用（如恶心、呕吐、流涎、躁动和屏气）的发生率低于电针组和盐酸达克罗宁胶浆组（分别为P<0.05和P<0.01）。此外，联合治疗组胃镜通过幽门时以及检查后心率和血氧饱和度的变化优于电针组和盐酸达克罗宁胶浆组（P<0.01）。联合治疗组恶心和呕吐的VAS值、首次通过成功率和检查持续时间也优于其他两组（P<0.05和P<0.01）。
电针联合盐酸达克罗宁胶浆局部麻醉可减轻胃镜检查期间的副作用，减轻患者痛苦，提高检查效率。
