Division of Urology of Department of Surgery, Faculty of Medical Sciences, Hospital de Clinicas, University of Campinas - UNICAMP, Rua Vital Brazil, 250, Campinas, SP, 13083-590, Brazil.
BMC Urol. 2021 Mar 10;21(1):35. doi: 10.1186/s12894-020-00730-2.
Infection is the most feared complication of a penile prosthesis. Diabetes mellitus (DM) is widely known to increase the risk of several infections, but its role in the penile prosthesis is still controversial. This systematic review aims to show the contemporary scenario of penile prosthesis infection and present a meta-analysis about DM contribution to penile prosthesis infection.
The review was performed with no language or time limitation, including ten databases. The included articles were about the male population who received a penile prosthesis with no model restriction, with a minimum follow up of 1 year, and outcomes adequately reported.
The mean infection incidence of penile prosthesis ranged from 0.33 to 11.4%. In early 2000, the general incidence of infection was 3 to 5%, then, the introduction of coated materials decreased it to 0.3 to 2.7%. The meta-analysis showed that diabetes mellitus is related to an increased risk of penile prosthesis infection with an odds ratio of 1.53 (95% CI 1.15-2.04).
Penile prosthesis infection decreased in the last decades but remains a significant cause of reoperation, and it is related to lower prosthesis survival. Meta-analysis concludes that diabetes mellitus is related to a higher risk of penile prosthesis infection.
感染是阴茎假体最令人担忧的并发症。众所周知，糖尿病（DM）会增加多种感染的风险，但它在阴茎假体中的作用仍存在争议。本系统评价旨在展示阴茎假体感染的当代情况，并进行荟萃分析，探讨 DM 对阴茎假体感染的影响。
本综述无语言和时间限制，共纳入了 10 个数据库。纳入的文章均为接受阴茎假体植入的男性人群，无假体型号限制，随访时间至少 1 年，且结果报告充分。
阴茎假体感染的发生率平均为 0.33%至 11.4%。21 世纪初，感染的总体发生率为 3%至 5%，随后，涂层材料的引入将其降低至 0.3%至 2.7%。荟萃分析显示，糖尿病与阴茎假体感染风险增加相关，比值比（OR）为 1.53（95%置信区间（CI）为 1.15-2.04）。
尽管过去几十年来阴茎假体感染的发生率有所下降，但它仍然是导致再次手术的重要原因，且与较低的假体存活率相关。荟萃分析得出结论，糖尿病与阴茎假体感染风险增加相关。
