Department of Optometry & Vision Science, Daegu Catholic University, Gyeongsan, 38430, South Korea.
J Nanosci Nanotechnol. 2021 Sep 1;21(9):4649-4653. doi: 10.1166/jnn.2021.19291.
This study prepared silicone hydrogel ophthalmic lenses using 2-hydroxyethylmethacrylate (HEMA), synthesized silicone monomer (SID), dimethylarsinic acid (DMA), -hydroxyethyl acrylamide (HEA), ethylene glycol dimethacrylate (a crosslinking agent, EGDMA), and azobisisobutyronitrile (an initiator, AIBN). Also, Zirconium oxide (ZrO₂), antimony tin oxide (ATO) nanoparticles were added to the silicone hydrogel material to analyze the characteristics of the nanoparticles. The mixture was heated at 130 °C for 2 hours to produce the ophthalmic contact lens by cast mould method. As a result, the manufactured silicone hydrogel lens was prepared having high oxygen permeability and tensile strength while satisfying the basic requirements of ophthalmic hydrogel lens materials. Also, the addition of ZrO₂ NPs increased tensile strength of the manufactured lens, and ATO NPs were found to improve wettability. Therefore, ZrO₂ and ATO nanoparticles can be used effectively as additives for functional ophthalmic silicone hydrogel lenses.
本研究使用 2-羟乙基甲基丙烯酸酯（HEMA）、合成硅单体（SID）、二甲砷酸（DMA）、-羟乙基丙烯酰胺（HEA）、乙二醇二甲基丙烯酸酯（交联剂，EGDMA）和偶氮二异丁腈（引发剂，AIBN）制备了硅水凝胶隐形眼镜。此外，还将氧化锆（ZrO₂）、氧化锑锡（ATO）纳米粒子添加到硅水凝胶材料中，以分析纳米粒子的特性。将混合物在 130°C 下加热 2 小时，通过浇铸模具法生产出隐形眼镜。结果，所制备的硅水凝胶镜片具有高透氧率和拉伸强度，同时满足眼科水凝胶镜片材料的基本要求。此外，ZrO₂ NPs 的添加提高了所制备镜片的拉伸强度，而 ATO NPs 则提高了润湿性。因此，ZrO₂ 和 ATO 纳米粒子可以有效地用作功能性眼科硅水凝胶隐形眼镜的添加剂。
