• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

基于聚（乙二醇）甲基醚甲基丙烯酸酯的水凝胶和二氧化铈纳米颗粒作为眼科镜片材料

Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material.

作者信息

Lee Min-Jae, Park Seon-Young, Sung A-Young

机构信息

Department of Optometry, Jeju Tourism University, Jeju 63063, Korea.

Department of Optometry & Vision Science, Daegu Catholic University, Gyeongsan 38430, Korea.

出版信息

Micromachines (Basel). 2021 Sep 16;12(9):1111. doi: 10.3390/mi12091111.

DOI:10.3390/mi12091111
PMID:34577754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8471772/
Abstract

The functional hydrogel lens containing 2-hydroxyethylmethacrylate (HEMA) was manufactured by thermal polymerization. The physical properties of the produced hydrogel lens were measured and analyzed. In this study, HEMA, ethylene glycol dimethacrylate (EGDMA), and azobisisobutyronitrile (AIBN) were used for thermal copolymerization. Additionally, poly (ethylene glycol) methyl ether methacrylate (PEGMEMA), 3-(Triethoxysilyl) propyl isocyanate (TEPI), and cerium(Ⅳ) oxide nanoparticles were used as additives to make a functional hydrogel lens. The mixture was heated at 100 °C for 90 min to produce the hydrogel ophthalmic lens by the cast mold method. The resulting physical properties showed that the water content and refractive index of the sample were in the ranges of 38.0642.11% and 1.4261.436, respectively. The addition of cerium oxide nanoparticles lowered the contact angle and allowed the hydrogel lens to block UV light. The tensile strength was also improved by 52.13% through cerium oxide nanoparticles, and up to 123.4% by using TEPI. Based on the results of this study, the produced ophthalmic lens is suitable for durable, UV-blocking high-performance lenses.

摘要

含甲基丙烯酸羟乙酯（HEMA）的功能性水凝胶镜片通过热聚合制备。对制得的水凝胶镜片的物理性能进行了测量和分析。在本研究中，甲基丙烯酸羟乙酯（HEMA）、乙二醇二甲基丙烯酸酯（EGDMA）和偶氮二异丁腈（AIBN）用于热共聚。此外，聚（乙二醇）甲基醚甲基丙烯酸酯（PEGMEMA）、3-（三乙氧基甲硅烷基）丙基异氰酸酯（TEPI）和氧化铈纳米颗粒用作添加剂以制备功能性水凝胶镜片。将混合物在100℃加热90分钟，通过浇铸模具法制备水凝胶眼科镜片。所得物理性能表明，样品的含水量和折射率分别在38.06%至42.11%和1.426至1.436的范围内。氧化铈纳米颗粒的添加降低了接触角，并使水凝胶镜片能够阻挡紫外线。通过氧化铈纳米颗粒，拉伸强度也提高了52.13%，使用TEPI时提高了123.4%。基于本研究结果，制得的眼科镜片适用于耐用、防紫外线的高性能镜片。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/34439b7045a2/micromachines-12-01111-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/3d7cc018b18d/micromachines-12-01111-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/db0be501b58f/micromachines-12-01111-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/08cb29fb4dea/micromachines-12-01111-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/311fd7c69600/micromachines-12-01111-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/d9660291ee04/micromachines-12-01111-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/4e7a2bc7b8f6/micromachines-12-01111-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/c4950cc533cf/micromachines-12-01111-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/d814c32b979e/micromachines-12-01111-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/d0aab4ebc759/micromachines-12-01111-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/34439b7045a2/micromachines-12-01111-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/3d7cc018b18d/micromachines-12-01111-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/db0be501b58f/micromachines-12-01111-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/08cb29fb4dea/micromachines-12-01111-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/311fd7c69600/micromachines-12-01111-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/d9660291ee04/micromachines-12-01111-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/4e7a2bc7b8f6/micromachines-12-01111-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/c4950cc533cf/micromachines-12-01111-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/d814c32b979e/micromachines-12-01111-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/d0aab4ebc759/micromachines-12-01111-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89cd/8471772/34439b7045a2/micromachines-12-01111-g010.jpg

相似文献

1
Poly (Ethylene Glycol) Methyl Ether Methacrylate-Based Hydrogel and Cerium(IV) Oxide Nanoparticles as Ophthalmic Lens Material.基于聚（乙二醇）甲基醚甲基丙烯酸酯的水凝胶和二氧化铈纳米颗粒作为眼科镜片材料
Micromachines (Basel). 2021 Sep 16;12(9):1111. doi: 10.3390/mi12091111.
2
Preparation and Characterization of Functional Ophthalmic Polymer Containing Nanoparticles Using Heat Treatment Method After Polymerization.聚合后采用热处理方法制备和表征含纳米粒子的功能性眼科聚合物。
J Nanosci Nanotechnol. 2019 Aug 1;19(8):4495-4502. doi: 10.1166/jnn.2019.16690.
3
Preparation and Analysis of Functional Silicone Hydrogel Lenses Containing ZrO₂ and Antimony Tin Oxide Nanoparticles.ZrO₂ 和掺锑氧化锡纳米颗粒功能硅水凝胶隐形眼镜的制备与分析。
J Nanosci Nanotechnol. 2021 Sep 1;21(9):4649-4653. doi: 10.1166/jnn.2021.19291.
4
Ophthalmic Hydrogel Contact Lens Material Containing Magnesium Oxide Nanoparticles and 3-(Trifluoromethyl)styrene for Biomedical Application.用于生物医学应用的含氧化镁纳米颗粒和3-(三氟甲基)苯乙烯的眼科水凝胶隐形眼镜材料
Micromachines (Basel). 2022 Nov 2;13(11):1897. doi: 10.3390/mi13111897.
5
Effect of Graphene Nanoparticles on the Physical Properties of Ophthalmic Polymer Containing Pyrrolidone Group.含吡咯烷酮基团的眼科用聚合物中石墨烯纳米粒子对物理性能的影响。
J Nanosci Nanotechnol. 2019 Oct 1;19(10):6516-6523. doi: 10.1166/jnn.2019.17074.
6
Preparation and Characterization of High Functional Ophthalmic Lens Material Containing Acrylic Formation Isocyanate Group with Carbon Nanoparticles.含碳纳米粒子的含丙烯酰基异氰酸酯基团的高功能性眼科透镜材料的制备与表征。
J Nanosci Nanotechnol. 2019 Oct 1;19(10):6225-6231. doi: 10.1166/jnn.2019.17036.
7
Effects on the Physical Properties of Ophthalmic Hydrogels Containing 4-Chlorostyrene and Cerium Oxide Nanoparticles with Ultraviolet Blocking Ability.含有具有紫外线阻断能力的 4-氯苯乙烯和氧化铈纳米颗粒的眼科水凝胶的物理性能的影响。
J Nanosci Nanotechnol. 2020 Nov 1;20(11):6871-6876. doi: 10.1166/jnn.2020.18812.
8
Preparation and Characterization of Ophthalmic Lens Materials Containing Titanium Silicon Oxide and Silver Nanoparticles.含钛硅氧化物和银纳米颗粒的眼科镜片材料的制备与表征
J Nanosci Nanotechnol. 2015 Oct;15(10):8016-22. doi: 10.1166/jnn.2015.11240.
9
Effect of Metal Oxide Nanoparticles on Silicone-Acrylate Copolymer Containing 1,3-Bis(3-aminopropyl)tetramethyldisiloxane.金属氧化物纳米粒子对含 1,3-双(3-氨丙基)四甲基二硅氧烷的硅丙共聚物的影响。
J Nanosci Nanotechnol. 2020 Aug 1;20(8):4753-4760. doi: 10.1166/jnn.2020.17818.
10
Copolymerization of Acrylic Monomers and Silane Group Containing Titanium Carbide Nanoparticles for Application to Ophthalmic Lens Materials.用于眼科镜片材料的含硅烷基团碳化钛纳米粒子的丙烯酸单体共聚。
J Nanosci Nanotechnol. 2021 Aug 1;21(8):4388-4393. doi: 10.1166/jnn.2021.19432.

本文引用的文献

1
CeO Nanoparticle-Containing Polymers for Biomedical Applications: A Review.用于生物医学应用的含CeO纳米颗粒聚合物：综述
Polymers (Basel). 2021 Mar 17;13(6):924. doi: 10.3390/polym13060924.
2
Cerium Oxide Nanoparticles: Recent Advances in Tissue Engineering.氧化铈纳米颗粒：组织工程学的最新进展
Materials (Basel). 2020 Jul 9;13(14):3072. doi: 10.3390/ma13143072.
3
Therapeutic Contact Lens for Scavenging Excessive Reactive Oxygen Species on the Ocular Surface.治疗性接触镜清除眼表过量活性氧。
ACS Nano. 2020 Feb 25;14(2):2483-2496. doi: 10.1021/acsnano.9b10145. Epub 2020 Jan 22.
4
Ophthalmic Applications of Cerium Oxide Nanoparticles.氧化铈纳米粒子在眼科中的应用。
J Ocul Pharmacol Ther. 2020 Jul/Aug;36(6):376-383. doi: 10.1089/jop.2019.0105. Epub 2019 Dec 5.
5
Dispersion and surface functionalization of oxide nanoparticles for transparent photocatalytic and UV-protecting coatings and sunscreens.用于透明光催化和紫外线防护涂层及防晒霜的氧化物纳米颗粒的分散与表面功能化
Sci Technol Adv Mater. 2013 Apr 26;14(2):023001. doi: 10.1088/1468-6996/14/2/023001. eCollection 2013 Apr.
6
UV-shielding property, photocatalytic activity and photocytotoxicity of ceria colloid solutions.氧化铈胶体溶液的遮光性能、光催化活性和光细胞毒性。
J Photochem Photobiol B. 2011 Jan 10;102(1):32-8. doi: 10.1016/j.jphotobiol.2010.09.002. Epub 2010 Sep 21.
7
Ultraviolet-B phototoxicity and hypothetical photomelanomagenesis: intraocular and crystalline lens photoprotection.紫外线-B 光毒性和假设的光致黑素瘤发生：眼内和晶状体的光保护。
Am J Ophthalmol. 2010 Apr;149(4):543-9. doi: 10.1016/j.ajo.2009.11.028.
8
Antibiotic resistance of bacterial biofilms.细菌生物膜的抗生素耐药性。
Int J Antimicrob Agents. 2010 Apr;35(4):322-32. doi: 10.1016/j.ijantimicag.2009.12.011. Epub 2010 Feb 10.
9
Hydrogel blends of chitin/chitosan, fucoidan and alginate as healing-impaired wound dressings.壳聚糖/几丁聚糖、褐藻胶和海藻酸钠水凝胶混合物作为治疗受损伤口的敷料。
Biomaterials. 2010 Jan;31(1):83-90. doi: 10.1016/j.biomaterials.2009.09.031. Epub 2009 Sep 22.
10
Anti-infective photodynamic biomaterials for the prevention of intraocular lens-associated infectious endophthalmitis.用于预防人工晶状体相关感染性眼内炎的抗感染光动力生物材料。
Biomaterials. 2009 Feb;30(4):597-602. doi: 10.1016/j.biomaterials.2008.10.015. Epub 2008 Nov 8.