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[维生素D在小儿肠易激综合征中的作用]

[Role of vitamin D in pediatric irritable bowel syndrome].

作者信息

Wen Yi, Jiang Mi-Zu

机构信息

Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine/National Clinical Research Center for Child Health/National Children's Regional Medical Center, Hangzhou 310052, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2021 Mar;23(3):310-314. doi: 10.7499/j.issn.1008-8830.2012080.

Abstract

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disease in children and has the clinical manifestations of recurrent abdominal pain with the changes in defecation frequency or stool form. Many studies have shown that children with IBS have a significantly lower vitamin D level than the healthy population, and vitamin D supplementation can significantly improve the clinical symptoms and quality of life of the children, suggesting that vitamin D supplementation may play a role in the treatment of IBS. This article reviews the association between vitamin D and IBS in children and elaborates on the possible mechanism of action of vitamin D.

摘要

肠易激综合征(IBS)是儿童常见的功能性胃肠疾病,具有反复腹痛并伴有排便频率或粪便形态改变的临床表现。许多研究表明,IBS患儿的维生素D水平显著低于健康人群,补充维生素D可显著改善患儿的临床症状和生活质量,提示补充维生素D可能在IBS的治疗中发挥作用。本文综述了儿童维生素D与IBS之间的关联,并阐述了维生素D可能的作用机制。

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[Role of vitamin D in pediatric irritable bowel syndrome].[维生素D在小儿肠易激综合征中的作用]
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本文引用的文献

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Vitamin D supplementation: upper limit for safety revisited?维生素 D 补充:安全性上限重新审视?
Aging Clin Exp Res. 2021 Jan;33(1):19-24. doi: 10.1007/s40520-020-01678-x. Epub 2020 Aug 28.
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Vitamin D, Autoimmune Disease and Rheumatoid Arthritis.维生素 D、自身免疫性疾病和类风湿关节炎。
Calcif Tissue Int. 2020 Jan;106(1):58-75. doi: 10.1007/s00223-019-00577-2. Epub 2019 Jul 8.
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The Brain-Gut-Microbiome Axis.脑-肠-微生物群轴
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