Wen Yi, Jiang Mi-Zu
Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine/National Clinical Research Center for Child Health/National Children's Regional Medical Center, Hangzhou 310052, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2021 Mar;23(3):310-314. doi: 10.7499/j.issn.1008-8830.2012080.
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disease in children and has the clinical manifestations of recurrent abdominal pain with the changes in defecation frequency or stool form. Many studies have shown that children with IBS have a significantly lower vitamin D level than the healthy population, and vitamin D supplementation can significantly improve the clinical symptoms and quality of life of the children, suggesting that vitamin D supplementation may play a role in the treatment of IBS. This article reviews the association between vitamin D and IBS in children and elaborates on the possible mechanism of action of vitamin D.
肠易激综合征（IBS）是儿童常见的功能性胃肠疾病，具有反复腹痛并伴有排便频率或粪便形态改变的临床表现。许多研究表明，IBS患儿的维生素D水平显著低于健康人群，补充维生素D可显著改善患儿的临床症状和生活质量，提示补充维生素D可能在IBS的治疗中发挥作用。本文综述了儿童维生素D与IBS之间的关联，并阐述了维生素D可能的作用机制。
