关于抗亚细胞胸腺细胞组分的异种抗血清作用的研究。
Studies on the effects of heterologous antisera against subcellular thymocyte fraction.
作者信息
Yamamoto H, Konomi K, Deodhar S D
出版信息
Jpn J Surg. 1977 Sep;7(3):158-64. doi: 10.1007/BF02469347.
PMID:336945
Abstract
Subcellular fractions of mice thymocytes were used for sensitization of rabbits. The antisera were examined for their immunosuppressive potency in vivo by allogeneic murine tumor metastases system and on skingraft survival and in vitro by leukocyte agglutination tests. The results indicated that the most potent immunosuppressive antisera was that against the second fraction (Fr. 2) of the detergent soluble endoplasmic reticulum fraction from thymocytes.
摘要
小鼠胸腺细胞的亚细胞组分用于使家兔致敏。通过同种异体小鼠肿瘤转移系统、皮肤移植存活情况在体内检测抗血清的免疫抑制效力，并通过白细胞凝集试验在体外进行检测。结果表明，最有效的免疫抑制抗血清是针对胸腺细胞去污剂可溶性内质网组分的第二部分（Fr. 2）的抗血清。
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