一名儿童的麦普替林中毒病例。

Maprotiline poisoning in a child.

作者信息

Peverini R, Ashwal S, Petry E

机构信息

Department of Pediatrics, Loma Linda University School of Medicine, CA 92350.

出版信息

Am J Emerg Med. 1988 May;6(3):247-9. doi: 10.1016/0735-6757(88)90010-1.

DOI:10.1016/0735-6757(88)90010-1

PMID:3370102

Abstract

A 6-year-old girl presented with tonic-clonic seizures and generalized convulsions lasting several minutes. A serum drug screen revealed maprotiline, and the estimated intake was 12 mg/kg. Despite initial neurologic impairment on discharge, follow-up 6 months later showed normal neurologic function in the patient. This report describes that case and discusses the toxicity associated with maprotiline and its management.

摘要

一名6岁女孩出现强直阵挛性癫痫发作和全身性惊厥，持续数分钟。血清药物筛查显示有马普替林，估计摄入量为12毫克/千克。尽管出院时最初有神经功能损害，但6个月后的随访显示该患者神经功能正常。本报告描述了该病例，并讨论了与马普替林相关的毒性及其处理方法。