Peverini R, Ashwal S, Petry E
Department of Pediatrics, Loma Linda University School of Medicine, CA 92350.
Am J Emerg Med. 1988 May;6(3):247-9. doi: 10.1016/0735-6757(88)90010-1.
A 6-year-old girl presented with tonic-clonic seizures and generalized convulsions lasting several minutes. A serum drug screen revealed maprotiline, and the estimated intake was 12 mg/kg. Despite initial neurologic impairment on discharge, follow-up 6 months later showed normal neurologic function in the patient. This report describes that case and discusses the toxicity associated with maprotiline and its management.
一名6岁女孩出现强直阵挛性癫痫发作和全身性惊厥,持续数分钟。血清药物筛查显示有马普替林,估计摄入量为12毫克/千克。尽管出院时最初有神经功能损害,但6个月后的随访显示该患者神经功能正常。本报告描述了该病例,并讨论了与马普替林相关的毒性及其处理方法。