致命性麦普替林中毒。
Fatal maprotiline intoxication.
作者信息
Curtis R A, Giacona N, Burrows D, Bauman J L, Schaffer M
出版信息
Drug Intell Clin Pharm. 1984 Sep;18(9):716-20. doi: 10.1177/106002808401800908.
PMID:6479020
Abstract
We report a fatal case of drug toxicity associated with torsade de pointes following an overdose of the tetracyclic antidepressant, maprotiline (Ludiomil). Tissue and plasma levels were obtained at autopsy and are noted. In addition, the cardiovascular effects, pharmacokinetics, and toxicity of maprotiline are reviewed and compared with that of tricyclic antidepressants.
摘要
我们报告了一例因过量服用四环类抗抑郁药马普替林（路滴美）导致药物毒性并伴有尖端扭转型室速的致死病例。尸检时获取了组织和血浆水平并做了记录。此外，对马普替林的心血管效应、药代动力学及毒性进行了综述，并与三环类抗抑郁药进行了比较。
相似文献
1
Fatal maprotiline intoxication.致命性麦普替林中毒。
Drug Intell Clin Pharm. 1984 Sep;18(9):716-20. doi: 10.1177/106002808401800908.
2
Left anterior hemiblock, complete right bundle branch block and sinus tachycardia in maprotiline poisoning.米普明中毒时出现左前半阻滞、完全性右束支传导阻滞及窦性心动过速。
Intensive Care Med. 1985;11(4):220-2. doi: 10.1007/BF00272410.
3
Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline.四环类抗抑郁药麦普替林引起的Q-T间期延长和尖端扭转型室性心动过速。
Am J Cardiol. 1983 Mar 1;51(5):904-6. doi: 10.1016/s0002-9149(83)80155-6.
4
[Fatal self-poisoning with the tetracyclic antidepressive drug, ludiomil (author's transl)].四环类抗抑郁药路滴美导致的致命性自我中毒（作者译）
Wien Klin Wochenschr. 1975 Apr 4;87(7):254-8.
5
[Heart conduction disorders in acute maprotiline poisoning].[急性麦普替林中毒时的心脏传导障碍]
Ann Fr Anesth Reanim. 1986;5(6):623-4. doi: 10.1016/s0750-7658(86)80077-6.
6
A fatal maprotiline intoxication.一例致命的麦普替林中毒。
Am J Forensic Med Pathol. 1985 Mar;6(1):45-7. doi: 10.1097/00000433-198503000-00009.
7
Maprotiline poisoning in a child.一名儿童的麦普替林中毒病例。
Am J Emerg Med. 1988 May;6(3):247-9. doi: 10.1016/0735-6757(88)90010-1.
8
Seizures due to maprotiline overdose.因米安色林过量导致的癫痫发作。
Ann Emerg Med. 1984 Jun;13(6):468-70. doi: 10.1016/s0196-0644(84)80016-5.
9
[Hepatitis following acute intoxication with maprotiline (Ludiomil)].[米安色林（路滴美）急性中毒后肝炎]
J Toxicol Clin Exp. 1985 Mar-Apr;5(2):121-3.
10
Relative toxicity of cyclic antidepressants.
Ann Emerg Med. 1986 Jul;15(7):797-804. doi: 10.1016/s0196-0644(86)80375-4.
引用本文的文献
1
Cardiotoxicity associated with an intentional overdose of maprotiline and perphenazine: a case report.与故意过量服用马普替林和奋乃静相关的心脏毒性：一例报告。
Can Fam Physician. 1987 Nov;33:2627-32.
Zotero 插件