[基于广义伊辛模型对具有2种配体的变构多聚酶动力学的描述]
[Description of the kinetics of allosteric polymeric enzymes with 2 ligands based on the generalized Ising model].
作者信息
Cherepanov D A
出版信息
Biofizika. 1988 Jan-Feb;33(1):41-5.
PMID:3370238
Abstract
The two-ligand model for allosteric regulation of complex polymeric enzymes is offered. Two types of cooperative interactions are observed--the cooperative transformations inside the promoter and interactions of promoters themselves--along with the direct interaction of two ligands inside each subunit. The solution of the model is given and its kinetic properties are discussed.
摘要
提出了复杂聚合酶变构调节的双配体模型。观察到两种协同相互作用——启动子内部的协同转变和启动子自身的相互作用——以及每个亚基内两个配体的直接相互作用。给出了该模型的解并讨论了其动力学性质。
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