Lagrange J L, Hoch M, Courdi A, Darcourt J, Benoiel J, Namer M, Hery M, Abbes M, Monticelli J, Schneider M
Département de radiothérapie, Centre Antoine-Lacassagne, Nice, France.
Bull Cancer. 1988;75(3):271-80.
To evaluate the utility of bone scans for the follow-up of patients with small breast cancers (T less than or equal to 3 cm), the files for 133 patients whose disease was diagnosed between Jan. 1, 1979 and Dec. 31, 1980 were reviewed. At initial presentation, two of these patients already had bone metastases. During their disease course, 30 patients developed metastases and 16 of them had at least one bone metastasis. In 7 of these 16 cases, the bone metastasis was solitary; in 4 cases bone lesions were symptomatic. A total of 178 bone scans were performed during the follow-up of these 133 patients; 16 of these scans were positive, but only 4 examinations allowed the diagnosis of bone metastasis. Despite the slight prognostic value of initial bone scanning in this series, the technique is of little value unless it is combined with clinical examinations aimed at early detection of disease recurrence or metastasis. Except as part of clinical trial protocols, systematic bone scans appear unnecessary for the staging and follow-up of patients with small breast cancers.
为评估骨扫描对小乳腺癌（T≤3cm）患者随访的作用，我们回顾了1979年1月1日至1980年12月31日期间确诊疾病的133例患者的病历。初次就诊时，其中2例患者已有骨转移。在疾病过程中，30例患者发生转移，其中16例至少有一处骨转移。在这16例中的7例，骨转移为孤立性；4例骨病变有症状。在这133例患者的随访期间共进行了178次骨扫描；其中16次扫描为阳性，但只有4次检查可诊断为骨转移。尽管在本系列中初始骨扫描有轻微的预后价值，但该技术价值不大，除非它与旨在早期发现疾病复发或转移的临床检查相结合。除作为临床试验方案的一部分外，对于小乳腺癌患者的分期和随访，系统性骨扫描似乎没有必要。
