小鼠味觉细胞中感受器电位的电压钳和电流钳记录。
Voltage- and current-clamp recordings of the receptor potential in mouse taste cell.
作者信息
Tonosaki K, Funakoshi M
机构信息
Department of Oral Physiology, School of Dentistry, Asahi University, Gifu, Japan.
出版信息
Brain Res. 1988 Apr 5;445(2):363-6. doi: 10.1016/0006-8993(88)91200-0.
PMID:3370469
Abstract
Intracellular recordings were obtained using the current-clamp and voltage-clamp techniques. When the taste cell membrane was voltage-clamped, the sucrose stimulus induced an inward current accompanied by a membrane resistance increase while the NaCl stimulus induced an inward current accompanied by a membrane resistance decrease. These phenomena indicated that sucrose and NaCl have quite a different generation mechanism of taste responses.
摘要
使用电流钳和电压钳技术进行细胞内记录。当味觉细胞膜被电压钳制时，蔗糖刺激诱导出内向电流，同时伴有膜电阻增加，而氯化钠刺激诱导出内向电流，同时伴有膜电阻降低。这些现象表明，蔗糖和氯化钠的味觉反应产生机制有很大不同。
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