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腭裂综合征和非综合征患者腭咽闭合不全的 Z 成形术腭再修复。

Palatal Re-Repair With Z-Plasty in Treatment of Velopharyngeal Insufficiency of Syndromic and Nonsyndromic Patients With Cleft Palate.

机构信息

Cleft and Craniofacial Center, Department of Plastic Surgery, Helsinki University Hospital and University of Helsinki, Finland.

出版信息

J Craniofac Surg. 2021;32(2):685-690. doi: 10.1097/SCS.0000000000007343.

Abstract

BACKGROUND

Velopharyngeal insufficiency (VPI) often results from palatal shortening or insufficient levator function after cleft palate repair.

AIMS

To assess the efficacy of palatal re-repair with Z-plasty in treatment of VPI for patients with isolated cleft palate (ICP).

METHODS

This retrospective analysis comprised 130 consecutive patients who had ICP with VPI that required Z-plasty as secondary surgery between 2008 and 2017. Pre- and post-operative evaluation of velopharyngeal function was done perceptually and instrumentally by Nasometer.

RESULTS

Median patient age at Z-plasty was 6.8 years (range 3.0-20.1). Of the 130 patients, preoperatively VPI was severe in 73 (56%), mild-to-moderate in 55 (42%), and borderline in 2 (2%). Postoperatively, 105 (81%) of patients achieved adequate (normal or borderline) velopharyngeal competence and 16 (12%) required second operation for residual VPI. The success rate was 84% in nonsyndromic patients, 79% in nonsyndromic Pierre Robin sequence patients, and 58% in syndromic patients. In syndromic children, the speech outcome was significantly worse than in nonsyndromic children (P = 0.014). Complications included wound healing problems in 3 patients (2%), mild infection in 1 patient (1%), postoperative bleeding in 1 (1%), and postoperative fistula in 2 (2%).

CONCLUSION

Palatal re-repair with Z-plasty is a safe operation for VPI correction in patients with ICP with a success rate of 81%. In syndromic patients, the procedure did not seem to work as well as in nonsyndromic patients.

摘要

背景

腭裂修复后腭帆提肌功能不足或软腭过短可导致咽腔闭合不全(VPI)。

目的

评估腭裂修复术后 Z 成形术治疗单纯腭裂(ICP)伴发咽腔闭合不全(VPI)的疗效。

方法

本回顾性分析纳入 2008 年至 2017 年期间因 Z 成形术行二次腭裂修复的 130 例 ICP 伴 VPI 患者。通过 Nasometer 对患者的腭咽功能进行术前、术后的主观和客观评估。

结果

Z 成形术时患者的中位年龄为 6.8 岁(范围 3.0-20.1 岁)。130 例患者中,术前 VPI 严重者 73 例(56%)、轻度至中度者 55 例(42%)、临界者 2 例(2%)。术后,105 例(81%)患者腭咽闭合功能达到正常或临界水平,16 例(12%)患者因残余 VPI 需要二次手术。非综合征患者的成功率为 84%,非综合征性 Pierre Robin 序列患者为 79%,综合征患者为 58%。在综合征患儿中,手术效果明显不如非综合征患儿(P = 0.014)。并发症包括 3 例(2%)患者的伤口愈合问题、1 例(1%)轻度感染、1 例(1%)术后出血和 2 例(2%)术后瘘管。

结论

腭裂修复术后 Z 成形术是治疗 ICP 伴 VPI 的安全方法,成功率为 81%。在综合征患者中,该方法的效果似乎不如非综合征患者。

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