Mogenson G J, Wu M
Department of Physiology, University of Western Ontario, London, Canada.
Brain Res Bull. 1988 Feb;20(2):241-6. doi: 10.1016/0361-9230(88)90184-0.
A comparison was made of the contributions to locomotor activity of output projections of the subpallidal region to the mediodorsal thalamus (MD) and to the pedunculopontine nucleus (PPN). Locomotor activity elicited by injections of picrotoxin into the subpallidal region was reduced by the administration of procaine to the pedunculopontine nucleus but not by the administration of procaine to mediodorsal thalamus. Since the pedunculopontine nucleus is part of the mesencephalic locomotor region (MLR) it appears that subpallido-pedunculopontine projections contribute to the locomotor component of adaptive behaviors associated with limbic integrative activities.
对苍白球下区域向丘脑背内侧核（MD）和脚桥核（PPN）的输出投射对运动活动的贡献进行了比较。向苍白球下区域注射印防己毒素所引发的运动活动，通过向脚桥核注射普鲁卡因而降低，但向丘脑背内侧核注射普鲁卡因则没有这种效果。由于脚桥核是中脑运动区（MLR）的一部分，因此苍白球-脚桥核投射似乎对与边缘整合活动相关的适应性行为的运动成分有贡献。
