Ata H
Mikrobiyol Bul. 1977 Jul;11(3):431-9.
Following the immunosuppressive treatment, applied after renal transplantations, infectious diseases are seen more frequently. Inspite of more frequency of bacterial infections, they can usually be controlled because of their easier diagnosis and treatment. However the mycotic diseases are usually fatal because of their easier diagnosis and treatment. However the mycotic diseases are usually fatal because of the difficulty in their diagnosis and treatment. The immunosuppressive treatment agents are cytotoxic medicines, codticosteroids, antilymphocytic sera (or antithymocytic sera) and radiation. The mycotic infections, more often encountered are candidiasis, aspergillosis, nocardiosis, cryptococcosis and phycomycosis. There are certain medicines used today in the treatment of deep mycotic infections. These are amphotericine B, 5 fluorocytosine and imidazol derivatives.
肾移植后进行免疫抑制治疗后,感染性疾病更为常见。尽管细菌感染更为频繁,但由于其诊断和治疗相对容易,通常可以得到控制。然而,真菌疾病通常因其诊断和治疗困难而致命。免疫抑制治疗药物包括细胞毒性药物、皮质类固醇、抗淋巴细胞血清(或抗胸腺细胞血清)和放射治疗。更常遇到的真菌感染有念珠菌病、曲霉菌病、诺卡菌病、隐球菌病和藻菌病。目前有某些药物用于治疗深部真菌感染。这些药物是两性霉素B、5-氟胞嘧啶和咪唑衍生物。