1Speech-Language-Hearing Center, School of Foreign Languages, Shanghai Jiao Tong University, 800 Dong Chuan Rd., Minhang District, Shanghai, 200240, China.
2Department of Speech-Language-Hearing Sciences & Center for Neurobehavioral Development, University of Minnesota, Twin Cities, MN 55455, USA.
Multisens Res. 2020 Sep 15;33(8):865-901. doi: 10.1163/22134808-bja10016.
Multisensory integration (MSI) of emotion has been increasingly recognized as an essential element of schizophrenic patients' impairments, leading to the breakdown of their interpersonal functioning. The present review provides an updated synopsis of schizophrenics' MSI abilities in emotion processing by examining relevant behavioral and neurological research. Existing behavioral studies have adopted well-established experimental paradigms to investigate how participants understand multisensory emotion stimuli, and interpret their reciprocal interactions. Yet it remains controversial with regard to congruence-induced facilitation effects, modality dominance effects, and generalized vs specific impairment hypotheses. Such inconsistencies are likely due to differences and variations in experimental manipulations, participants' clinical symptomatology, and cognitive abilities. Recent electrophysiological and neuroimaging research has revealed aberrant indices in event-related potential (ERP) and brain activation patterns, further suggesting impaired temporal processing and dysfunctional brain regions, connectivity and circuities at different stages of MSI in emotion processing. The limitations of existing studies and implications for future MSI work are discussed in light of research designs and techniques, study samples and stimuli, and clinical applications.
多感觉信息整合（MSI）在情绪处理中被认为是精神分裂症患者功能障碍的一个重要因素，导致他们的人际交往能力受损。本综述通过检查相关的行为和神经科学研究，提供了精神分裂症患者在情绪处理中多感觉信息整合能力的最新概述。现有的行为研究采用了成熟的实验范式来研究参与者如何理解多感觉情绪刺激，并解释它们的相互作用。然而，对于一致性诱导的促进效应、模态优势效应以及广义或特定的损伤假说，仍然存在争议。这种不一致可能是由于实验操作、参与者的临床症状和认知能力的差异和变化所致。最近的电生理学和神经影像学研究揭示了事件相关电位（ERP）和大脑激活模式中的异常指标，进一步表明在情绪处理的不同阶段，时间处理受损和功能失调的脑区、连接和回路。根据研究设计和技术、研究样本和刺激以及临床应用，讨论了现有研究的局限性以及对未来多感觉信息整合工作的意义。
