Zhang Na, Hao Jiajie, Cai Yan, Wang Mingrong
State Key Laboratory of Molecular Oncology, Center for Cancer Precision Medicine, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Chin J Cancer Res. 2021 Feb 28;33(1):115-132. doi: 10.21147/j.issn.1000-9604.2021.01.12.
Secretory proteins in tumor tissues are important components of the tumor microenvironment. Secretory proteins act on tumor cells or stromal cells or mediate interactions between tumor cells and stromal cells, thereby affecting tumor progression and clinical treatment efficacy. In this paper, recent research advances in secretory proteins in malignant tumors are reviewed.
肿瘤组织中的分泌蛋白是肿瘤微环境的重要组成部分。分泌蛋白作用于肿瘤细胞或基质细胞,或介导肿瘤细胞与基质细胞之间的相互作用,从而影响肿瘤进展和临床治疗效果。本文综述了恶性肿瘤中分泌蛋白的最新研究进展。