Bharti Ram, Chopra Bhupinder Singh, Raut Sachin, Khatri Neeraj
IMTECH Centre for Animal Resources & Experimentation (iCARE), Council of Scientific and Industrial Research-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Front Pharmacol. 2021 Jan 27;11:582506. doi: 10.3389/fphar.2020.582506. eCollection 2020.
(Roxb. ex Willd.) DC. (Fabaceae), also known as Indian Kudzu (vidari kand), is a perennial herb distributed throughout India and other Asian countries. Traditionally, tuber and leaves of this plant have extensively been reported for nutritional and medicinal properties in Ayurveda as well as in Chinese traditional practices. The objective of the present review is to compile and update the published data on traditional uses, pharmacological potential, and phytochemistry of compounds isolated from the plant . extracts and its purified compounds possess multiple activities such as anticancer, anticonvulsant, antidiabetic, antifertility, anti-inflammatory, antioxidant, anti-stress, antiulcerogenic, cardioprotective, hypolipidemic, hepatoprotective, immunomodulatory, nephroprotective, nootropic, neuroprotective, and wound healing. Tuber and leaf extracts of contain several bioactive constituents such as puerarin, daidzein, genistein, quercetin, irisolidone, biochanin A, biochanin B, isoorientin, and mangiferin, which possess an extensive range of pharmacological activities. The extensive range of pharmacological properties of provides opportunities for further investigation and presents a new approach for the treatment of ailments. Many phytochemicals have been identified and characterized from ; however, some of them are still unexplored, and there is no supporting data for their activities and exact mechanisms of action. Therefore, further investigations are warranted to unravel the mechanisms of action of individual constituents of this plant.
(罗克斯伯里氏豆科植物)德堪多(豆科),也被称为印度葛藤(维达里坎德),是一种多年生草本植物,分布于印度和其他亚洲国家。传统上,这种植物的块茎和叶子在阿育吠陀医学以及中国传统医学中,因其营养和药用特性而被广泛报道。本综述的目的是汇编和更新已发表的关于该植物传统用途、药理潜力以及从中分离出的化合物的植物化学的相关数据。提取物及其纯化化合物具有多种活性,如抗癌、抗惊厥、抗糖尿病、抗生育、抗炎、抗氧化、抗应激、抗溃疡、心脏保护、降血脂、肝脏保护、免疫调节、肾脏保护、益智、神经保护和伤口愈合等。的块茎和叶子提取物含有几种生物活性成分,如葛根素、大豆苷元、染料木黄酮、槲皮素、鸢尾酮、鹰嘴豆芽素A、鹰嘴豆芽素B、异荭草素和芒果苷,它们具有广泛的药理活性。的广泛药理特性为进一步研究提供了机会,并为疾病治疗提供了新方法。已经从该植物中鉴定并表征了许多植物化学物质;然而,其中一些仍未被探索,且缺乏关于其活性和确切作用机制的支持数据。因此,有必要进一步研究以阐明该植物各个成分的作用机制。