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右半结肠切除术与左半结肠切除术后肠道功能恢复的差异可能归因于直肠乙状结肠的功能亢进。

Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity.

作者信息

Seo Sean Ho Beom, Bissett Ian, O'Grady Gregory

机构信息

Department of Surgery, University of Auckland, Auckland, New Zealand.

出版信息

Front Physiol. 2021 Feb 23;12:635167. doi: 10.3389/fphys.2021.635167. eCollection 2021.

Abstract

It is established that gut function recovers slower after right vs. left colectomies with higher rates of prolonged post-operative ileus (PPOI), but the reason is unclear. Development of PPOI is multifactorial. A recent manometry study in right colectomy patients showed that the distal colon becomes hyperactive after surgery with predominantly cyclic motor patterns (CMPs). In this perspective, we evaluate the hypothesis that the slower gut recovery after right hemicolectomy could be induced by a functional obstruction due to hyperactive CMPs.

摘要

已经确定,与左半结肠切除术相比,右半结肠切除术后肠道功能恢复较慢,术后肠梗阻延长(PPOI)的发生率较高,但其原因尚不清楚。PPOI的发生是多因素的。最近一项针对右半结肠切除术患者的测压研究表明,术后远端结肠变得活跃,主要表现为周期性运动模式(CMPs)。从这个角度来看,我们评估这样一个假设,即右半结肠切除术后肠道恢复较慢可能是由CMPs活跃导致的功能性梗阻引起的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/008d/7940204/26788f7b6d88/fphys-12-635167-g001.jpg

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