Pulmonology Department, Fattouma Bourguiba Hospital, Monastir, Tunisia.
Department of Pathology, Fattouma Bourguiba Hospital, Monastir, Tunisia.
Pan Afr Med J. 2019 Nov 8;34:137. doi: 10.11604/pamj.2019.34.137.14902. eCollection 2019.
Adenoid cystic carcinoma (ACC) is a rare malignant epithelial tumor that predominantly originates in the salivary glands. Primary ACC of the tracheobronchial tree is extremely rare. We report two new cases of central airways primary ACC: a 58 year-old male with an ACC of the left main bronchus who underwent a pneumonectomy with node dissection, and a 52 year-old female with proximal tracheal ACC presenting as asthma treated by surgical resection and a postoperative radiotherapy. Primary ACC of the tracheobronchial tree is often misdiagnosed given the non-specific clinical presentation. An early diagnosis is essential to ensure good outcomes. An interdisciplinary treatment is required based especially on surgery and radiotherapy.
腺样囊性癌（ACC）是一种罕见的恶性上皮肿瘤，主要起源于唾液腺。原发性气管支气管树 ACC 极为罕见。我们报告两例中央气道原发性 ACC 新病例：1 例 58 岁男性，左主支气管 ACC 行肺切除术及淋巴结清扫术；1 例 52 岁女性，近段气管 ACC 表现为哮喘，行手术切除和术后放疗。由于非特异性临床表现，原发性气管支气管树 ACC 常被误诊。早期诊断对于确保良好的预后至关重要。需要根据手术和放疗等方法进行跨学科治疗。
