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手术治疗的气管支气管腺样囊性癌病例的临床病理研究

Clinicopathological study of surgically treated cases of tracheobronchial adenoid cystic carcinoma.

作者信息

Shimizu Junzo, Oda Makoto, Matsumoto Isao, Arano Yoshihiko, Ishikawa Norihiko, Minato Hiroshi

机构信息

Department of Surgery, KKR Hokuriku Hospital, 2-13-43 Izumigaoka, Kanazawa, 921-8035, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2010 Feb;58(2):82-6. doi: 10.1007/s11748-009-0467-4. Epub 2010 Feb 13.

DOI:10.1007/s11748-009-0467-4
PMID:20155344
Abstract

Between 1980 and 2007, five patients were pathologically diagnosed as tracheobronchial adenoid cystic carcinoma (ACC). All five patients were women aged 37-67 years. Four tumors were located in the larger airways, and one tumor was located in the peripheral lung. The following operations were done: bronchoplastic procedures in three (carinal resection with doublebarreled carinoplasty in one, sleeve right pneumonectomy in one, sleeve middle lobectomy in one), left pneumonectomy in one, and left upper lobectomy in one. Three of the five patients have survived for 172, 144, and 10 months after surgery, respectively. The best local treatment for ACC of the major airway is considered to be sleeve resection of the trachea or bronchus in an area where airway reconstruction may not be disturbed and to add postoperative irradiation when there is residual carcinoma at the stump. However, it seems controversial to recommend adjuvant radiotherapy in all patients undergoing resection.

摘要

1980年至2007年间,有5例患者经病理诊断为气管支气管腺样囊性癌(ACC)。所有5例患者均为女性,年龄在37至67岁之间。4例肿瘤位于较大气道,1例肿瘤位于肺外周。实施了以下手术:3例行支气管成形术(1例行隆突切除及双筒隆突成形术,1例行袖状右肺切除术,1例行袖状中叶切除术),1例行左肺切除术,1例行左上叶切除术。5例患者中有3例分别在术后存活了172个月、144个月和10个月。对于主气道ACC的最佳局部治疗方法,被认为是在气道重建可能不受干扰的区域行气管或支气管袖状切除术,并且当残端有癌残留时加用术后放疗。然而,推荐对所有接受切除术的患者进行辅助放疗似乎存在争议。

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