Department of Radiology, Mayo Clinic, Jacksonville, FL, USA.
Department of Radiology, Division of Cardiothoracic Imaging, Mayo Clinic, Jacksonville, FL, USA.
J Radiol Case Rep. 2020 Oct 31;14(10):16-30. doi: 10.3941/jrcr.v14i10.4101. eCollection 2020 Oct.
Thymoma and paraganglioma are known causes of mediastinal masses, the latter being extremely rare. Thymomas arise from remnant thymic tissue in the anterior mediastinum; whereas, thoracic paragangliomas arise from para-aortic or para-vertebral sympathetic chain ganglion (derivatives of embryonic neural crest) in the middle or posterior mediastinum. We report a case of a middle-aged woman with two mediastinal masses, originally believed to be a single tumor or primary malignancy with adjacent metastasis on Computed Tomography (CT) that were further delineated with Magnetic Resonance Imaging (MRI) and [68Ga]-DOTA-(Tyr3)-octreotate (DOTA-TATE) Positron Emission Tomography-Computed Tomography (PET-CT) and surgical pathology as two distinct entities: left epicardial paraganglioma and anterior mediastinal thymoma. A comprehensive discussion of both entities is included.
胸腺瘤和副神经节瘤是纵隔肿块的已知病因，后者极为罕见。胸腺瘤起源于前纵隔的残余胸腺组织；而胸内副神经节瘤起源于中纵隔或后纵隔的主动脉旁或椎旁交感神经链节（胚胎神经嵴的衍生物）。我们报告了一例中年女性的两个纵隔肿块，最初在计算机断层扫描（CT）上被认为是单一肿瘤或原发性恶性肿瘤，伴有相邻转移，通过磁共振成像（MRI）和 [68Ga]-DOTA-（Tyr3）-奥曲肽（DOTA-TATE）正电子发射断层扫描-计算机断层扫描（PET-CT）进一步描绘，并通过手术病理检查确认为两个不同的实体：左心外膜副神经节瘤和前纵隔胸腺瘤。我们对这两个实体都进行了全面的讨论。
