From the Departments of Nuclear Medicine.
Pathology, Gazi Yaşargil Training and Research Hospital, University of Health Sciences, Diyarbakir, Turkey.
Clin Nucl Med. 2023 Jan 1;48(1):e40-e43. doi: 10.1097/RLU.0000000000004410. Epub 2022 Sep 28.
18F-FDG PET/CT performed for staging of colon cancer in a 60-year-old woman revealed a thymic neoplasm with increased radiopharmaceutical uptake in the anterior mediastinum. 68Ga-FAPI PET/CT showed low FAPI uptake in the anterior mediastinal mass. The patient was diagnosed with type B3 thymoma by histopathologic evaluation. In this case, thymoma demonstrated lower uptake with FAPI than FDG. Larger studies are required for the differentiation of malignant and benign mediastinal masses with FAPI.
60 岁女性行 18F-FDG PET/CT 分期检查结肠癌，结果显示前纵隔胸腺肿瘤摄取放射性药物增加。68Ga-FAPI PET/CT 显示前纵隔肿块 FAPI 摄取较低。患者经组织病理学评估诊断为 B3 型胸腺瘤。在本病例中，胸腺瘤对 FAPI 的摄取低于 FDG。需要更大规模的研究来区分 FAPI 摄取的良恶性纵隔肿块。
