Jackson A H, Jenkins R T, Grinstein M, Ferramola de Sancovich A M, Sancovich H A
Department of Chemistry, University College, Cardiff, Wales, UK.
Clin Chim Acta. 1988 Mar 15;172(2-3):245-52. doi: 10.1016/0009-8981(88)90330-0.
A purple pigment, phyriaviolin, and a blue pigment, phyriaazulin, have been found in relatively large amounts in the urine of patients suffering from two diverse pathological conditions, porphyria cutanea tarda and Crohn's disease. The two pigments have been characterised by chemical, spectroscopic, and chromatographic studies and identified to be indirubin and indigo (indigotin). Possible reasons for their formation are discussed.
在患有迟发性皮肤卟啉症和克罗恩病这两种不同病理状况的患者尿液中,发现了相对大量的一种紫色色素——紫卟啉素以及一种蓝色色素——蓝卟啉素。通过化学、光谱和色谱研究对这两种色素进行了表征,并确定它们为靛玉红和靛蓝(靛蓝素)。文中讨论了它们形成的可能原因。