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眼动脱敏再处理疗法治疗与医学相关的儿童和青少年阈下创伤后应激障碍的长期疗效:一项随机对照试验。

Long-term effectiveness of eye movement desensitization and reprocessing in children and adolescents with medically related subthreshold post-traumatic stress disorder: a randomized controlled trial.

机构信息

Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

Division of Cardiology, Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

出版信息

Eur J Cardiovasc Nurs. 2021 May 22;20(4):348-357. doi: 10.1093/eurjcn/zvaa006.

Abstract

AIMS

Medical procedures and hospitalizations can be experienced as traumatic and can lead to post-traumatic stress reactions. Eye movement desensitization and reprocessing (EMDR) shows promising results but very few long-term studies have been published. Therefore, our aim was to test the long-term (8 months post-treatment) effectiveness of EMDR in children and adolescents with medically related subthreshold post-traumatic stress disorder (PTSD).

METHODS AND RESULTS

Seventy-four children (including 39 with congenital or acquired heart disease) aged 4-15 (M = 9.6 years) with subthreshold PTSD after previous hospitalization were included into a parallel group randomized controlled trial. Participants were randomized to EMDR (n = 37) or care-as-usual (CAU) (n = 37; medical care only). The primary outcome was PTSD symptoms of the child. Secondary outcomes were symptoms of depression and blood-injection-injury (BII) phobia, sleep problems, and health-related quality of life (HrQoL) of the child. Assessments of all outcomes were planned at baseline and 8 weeks and 8 months after the start of EMDR/CAU. We hypothesized that the EMDR group would show significantly more improvements on all outcomes over time. Both groups showed improvements over time on child's symptoms of PTSD (only parent report), depression, BII phobia, sleep problems, and most HrQoL subscales. GEE analyses showed no significant differences between the EMDR group (nT2 = 33, nT3 = 30) and the CAU group (nT2 = 35, nT3 = 32) on the primary outcome. One superior effect of EMDR over time was found for reducing parent-reported BII phobia of the child.

CONCLUSION

EMDR did not perform better than CAU in reducing subthreshold PTSD up to 8 months post-treatment in previously hospitalized children. Possible explanations and clinical implications are discussed.

摘要

目的

医疗程序和住院治疗可能会被体验为创伤性的,并可能导致创伤后应激反应。眼动脱敏再处理(EMDR)显示出有希望的结果,但发表的长期研究很少。因此,我们的目的是测试 EMDR 在患有与医学相关的阈下创伤后应激障碍(PTSD)的儿童和青少年中的长期(治疗后 8 个月)疗效。

方法和结果

本研究纳入了 74 名儿童(包括 39 名患有先天性或后天性心脏病的儿童),年龄在 4-15 岁(M=9.6 岁),在之前的住院治疗后患有阈下 PTSD。参与者被随机分配到 EMDR(n=37)或常规护理(CAU)(n=37;仅提供医疗护理)组。主要结局是儿童的 PTSD 症状。次要结局是儿童的抑郁症状和血液-注射-伤害(BII)恐惧症、睡眠问题和健康相关生活质量(HrQoL)。所有结局的评估均计划在 EMDR/CAU 开始后的基线、8 周和 8 个月进行。我们假设 EMDR 组在所有结局上的改善将随着时间的推移更加显著。两组在 PTSD(仅父母报告)、抑郁、BII 恐惧症、睡眠问题和大多数 HrQoL 子量表的儿童症状上均随时间改善。GEE 分析显示,EMDR 组(nT2=33,nT3=30)和 CAU 组(nT2=35,nT3=32)在主要结局上无显著差异。随着时间的推移,EMDR 对减少父母报告的儿童 BII 恐惧症的效果更好。

结论

在之前住院的儿童中,EMDR 在治疗后 8 个月内降低阈下 PTSD 的效果并不优于 CAU。讨论了可能的解释和临床意义。

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