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经鼻内镜下新生儿双侧完全性后鼻孔闭锁修复术。

Endoscopic endonasal repair of complete bilateral choanal atresia in neonates.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany.

ENT Center, Dr. Lübbers & Kollegen, 82362, Weilheim, Germany.

出版信息

Eur J Pediatr. 2021 Jul;180(7):2245-2251. doi: 10.1007/s00431-021-04020-3. Epub 2021 Mar 11.

Abstract

Reported success rates of endoscopic choanal atresia (CA) surgery vary substantially due to a high heterogeneity in and between study groups. Comprehensive data on the unique patient cohort of newborns with bilateral CA are scarce. Our study aimed to close this gap by using narrow inclusion criteria and standardized surgical outcome parameters. A total of ten neonates who were diagnosed with bilateral complete CA and underwent endoscopic surgery at the Department of Otolaryngology, Head and Neck Surgery in the University Hospital of Munich between 2008 and 2017 were included. Preoperative findings, surgical procedures, outcome, and follow-up were analyzed. Standardized criteria were used to assess surgical outcome. Almost all patients (90%) required at least one revision procedure within the first 6 months after initial surgery because of symptomatic partial or complete restenosis. After that, all surviving patients remained asymptomatic until the end of the follow-up period.Conclusion: Endoscopic bilateral CA repair in neonates is a safe procedure with a high long-term success rate. However, compared to other patient groups with choanal obstruction, restenosis occurs frequently, and revision procedures are required in a large number of cases. This should be considered during preoperative planning and parent counseling. What is Known: • Bilateral complete choanal atresia (CA) is a neonatal emergency that requires surgical intervention. • Reported success rates of endoscopic choanal obstruction repair are highly variable and mostly derived from heterogenous study groups that do not reflect the situation in neonates adequately. What is New: • This study focuses exclusively on newborns with complete bilateral CA who underwent endoscopic surgery within the first 28 days of life and uses standardized criteria to assess outcome. • The long-term success rate of endoscopic bilateral CA repair in neonates is high; however, almost all patients require at least one revision procedure within the first 6 months.

摘要

内镜治疗后鼻孔闭锁(CA)的成功率报道差异较大,这主要是由于研究组之间存在高度异质性。关于双侧 CA 的新生儿这一独特患者群体的综合数据非常有限。我们的研究旨在通过使用严格的纳入标准和标准化的手术结果参数来填补这一空白。2008 年至 2017 年间,共有 10 名被诊断为双侧完全性 CA 并在慕尼黑大学医院耳鼻喉科接受内镜手术的新生儿纳入本研究。分析了术前发现、手术过程、结果和随访情况。使用标准化标准评估手术结果。几乎所有患者(90%)都需要在初次手术后的前 6 个月内至少进行一次修正手术,因为存在症状性部分或完全再狭窄。此后,所有存活患者在随访期结束时都无症状。结论:在新生儿中进行内镜双侧 CA 修复是一种安全的手术,具有较高的长期成功率。然而,与其他有后鼻孔阻塞的患者群体相比,再狭窄的发生率较高,在大量病例中需要进行修正手术。这在术前计划和家长咨询时应予以考虑。已知:•双侧完全性 CA 是一种需要手术干预的新生儿急症。•内镜治疗后鼻孔阻塞修复的成功率报道差异较大,且主要来源于不能充分反映新生儿情况的异质性研究组。新内容:•本研究专门针对在出生后 28 天内接受内镜手术的完全性双侧 CA 新生儿,使用标准化标准评估结果。•在新生儿中,内镜双侧 CA 修复的长期成功率较高;然而,几乎所有患者都需要在最初 6 个月内至少进行一次修正手术。

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