Zhou R H, Lin X D
National Research Institute for Family Planning, Beijing, China.
Contraception. 1988 Mar;37(3):239-45. doi: 10.1016/0010-7824(88)90026-1.
(-)-Gossypol has been isolated from cottonseed of G. barbadense L. Three Gossypium species were studied for the isolation. The study has also revealed a correlation between the optical activity of gossypol isolated and the species of cottonseed used. Gossypol isolated from the species G. barbadense is always found to be levorotatory caused by an excess of (-)-gossypol, whereas that from the species G. hirsutum is always dextrorotatory caused by an excess of (+)-gossypol. Results of most samples (cultivars) showed that optical purity of gossypol isolated from G. barbadense varied from 10-25%, while that from G. hirsutum varied from 10-20%. This is the first report of (-)-gossypol occurring naturally.
（-）-棉酚是从海岛棉的棉籽中分离出来的。为了进行分离，研究了三种棉属植物。该研究还揭示了所分离棉酚的旋光性与所用棉籽品种之间的相关性。从海岛棉品种中分离出的棉酚总是左旋的，这是由于（-）-棉酚过量所致，而从陆地棉品种中分离出的棉酚总是右旋的，这是由于（+）-棉酚过量所致。大多数样品（品种）的结果表明，从海岛棉中分离出的棉酚的光学纯度在10%-25%之间，而从陆地棉中分离出的棉酚的光学纯度在10%-20%之间。这是关于天然存在（-）-棉酚的首次报道。
