Department of Psychiatry and Behavioral Medicine, Center for AIDS Intervention Research.
Institute for Health and Equity, Medical College of Wisconsin, Milwaukee, WI.
Med Care. 2021 Apr 1;59(Suppl 2):S124-S131. doi: 10.1097/MLR.0000000000001336.
Providing permanent supportive housing to chronically homeless persons living with human immunodeficiency virus (PLH) contributes to improved human immunodeficiency virus (HIV) outcomes, including adherence to antiretroviral therapy (ART). This study seeks to understand whether certain components of housing, namely intensity of case management and specialized HIV housing programs, affects ART adherence for PLH in supportive housing.
From 2015 to 2019 we conducted quantitative assessments with 157 PLH in supportive housing at baseline, 6-, 12-, and 18-month postbaseline to identify factors associated with ART adherence. General Estimating Equations for repeated measures were performed to assess bivariate and multivariate measures.
Two thirds of PLH in supportive housing reported 95% or greater adherence to ART. Multivariate analyses indicate that neither intensity of case management services nor specialized housing for PLH were associated with greater ART adherence. Greater time since diagnosis was positively associated with ART adherence. Greater depressive symptoms and African American race were negatively associated with ART adherence.
Study findings reveal that although prior research has established the importance of receipt of housing for homeless PLH, the type or intensity of case management services associated with that housing may not be as important as simply being housed. Our results highlight the importance of considering mental health and more recent HIV diagnosis when developing treatment and case management plans to enhance residents' ART adherence.
为患有人类免疫缺陷病毒(PLH)的长期无家可归者提供永久性支持性住房有助于改善人类免疫缺陷病毒(HIV)的结果,包括抗逆转录病毒治疗(ART)的依从性。本研究旨在了解住房的某些组成部分,即个案管理的强度和专门的 HIV 住房计划,是否会影响支持性住房中 PLH 的 ART 依从性。
我们从 2015 年到 2019 年对 157 名住在支持性住房中的 PLH 进行了基线、6 个月、12 个月和 18 个月的定量评估,以确定与 ART 依从性相关的因素。重复测量的一般估计方程用于评估双变量和多变量措施。
三分之二的支持性住房中的 PLH 报告了 95%或更高的 ART 依从性。多变量分析表明,个案管理服务的强度或专门为 PLH 提供的住房与更高的 ART 依从性无关。诊断后时间越长与 ART 依从性呈正相关。更多的抑郁症状和非裔美国人种族与 ART 依从性呈负相关。
研究结果表明,尽管先前的研究已经确定了为无家可归的 PLH 提供住房的重要性,但与该住房相关的个案管理服务的类型或强度可能不如住房本身重要。我们的研究结果强调了在制定治疗和个案管理计划时考虑心理健康和最近的 HIV 诊断的重要性,以提高居民的 ART 依从性。