Division of Neurosurgery.
Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, Kingston Health Sciences Centre.
Otol Neurotol. 2021 Aug 1;42(7):1067-1073. doi: 10.1097/MAO.0000000000003107.
To investigate preoperative patient demographics and comorbidities in relation with postsurgical complications following vestibular schwannoma surgery.
Retrospective population-based cohort study.
All hospitals in the Canadian province of Ontario.
This study includes 1,456 patients who underwent vestibular schwannoma surgery from April 1, 2002 to March 31, 2018 in Ontario, Canada.
INTERVENTION/OUTCOME MEASURES: For all surgical patients, the demographic data, preoperative comorbidities, and postoperative complications were evaluated. Postoperative complications were examined immediately following surgery in the hospital as well as 1 year following the hospital discharge.
The most common comorbidities in this cohort were hypertension (30.22%), diabetes (9.48%), asthma (13.53%), and chronic obstructive pulmonary disease (6.73%). Diabetes was the most impactful comorbidity and was associated with higher risk of myocardial infarction (RR = 4.58, p < 0.01), pneumonia (RR = 1.80, p = 0.02), dysphagia (RR = 1.58, p < 0.01), and meningitis (RR = 3.62, p < 0.01). Analysis of surgical approaches revealed that the translabyrinthine approach, compared with the open craniotomy approach, was negatively associated with postoperative complications including pneumonia (RR = 0.43, p < 0.01), urinary tract infection (RR = 0.55, p = 0.01), dysphagia (RR = 0.66, p < 0.01), and readmission (RR = 0.45, p < 0.01).
This study examines patient demographics, preoperative comorbidities, and postoperative complications in patients who have undergone vestibular schwannoma surgery. The results highlight associations between patient characteristics and postoperative outcomes that can aid in preoperative decision-making and counselling.
研究与前庭神经鞘瘤手术后并发症相关的手术前患者人口统计学和合并症。
回顾性基于人群的队列研究。
加拿大安大略省所有医院。
这项研究包括 1456 名于 2002 年 4 月 1 日至 2018 年 3 月 31 日在加拿大安大略省接受前庭神经鞘瘤手术的患者。
干预/观察措施:对所有手术患者评估人口统计学数据、术前合并症和术后并发症。术后并发症在医院内手术后以及出院后 1 年内进行检查。
该队列中最常见的合并症是高血压(30.22%)、糖尿病(9.48%)、哮喘(13.53%)和慢性阻塞性肺疾病(6.73%)。糖尿病是最具影响力的合并症,与心肌梗死风险增加相关(RR=4.58,p<0.01)、肺炎(RR=1.80,p=0.02)、吞咽困难(RR=1.58,p<0.01)和脑膜炎(RR=3.62,p<0.01)。手术方法分析显示,与开颅手术相比,经迷路入路与术后肺炎(RR=0.43,p<0.01)、尿路感染(RR=0.55,p=0.01)、吞咽困难(RR=0.66,p<0.01)和再入院(RR=0.45,p<0.01)等并发症呈负相关。
本研究检查了接受前庭神经鞘瘤手术患者的患者人口统计学、术前合并症和术后并发症。结果突出了患者特征与术后结果之间的关联,有助于术前决策和咨询。