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后颅底手术后吞咽困难成人的危险因素与生活质量:一项横断面研究

Risk factors and quality of life in adults with dysphagia after posterior skull base surgery: a cross-sectional study.

作者信息

Wang Qiao, Cheng Shang-Jin, Duan Dan, Cui Wen-Yao, Liu Wen-Jie

机构信息

Department of Neurosurgery, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China.

出版信息

Front Oncol. 2025 Aug 29;15:1582176. doi: 10.3389/fonc.2025.1582176. eCollection 2025.

Abstract

INTRODUCTION

The study aimed to evaluate the current status of swallowing function and quality of life in patients undergoing posterior skull base surgery, identify risk factors for dysphagia, and provide evidence for early interventions.

METHOD

Patients undergoing posterior skull base surgery were prospectively enrolled, from June 2023 to June 2024. Data collection included demographics, disease-related details, swallowing function assessment, and scores of Swallowing-Quality of Life (SWAL-QOL). The logistic regression was used to identify risk factors influencing dysphagia, while the SWAL-QOL questionnaire was used to investigate the quality of life in patients undergoing posterior skull base surgery.

RESULTS

Among the 143 patients, approximately 50% developed postoperative dysphagia. Logistic regression analysis identified a history of choking, surgical duration, and the total score of nutritional risk as independent predictors of dysphagia. The area under the Receiver Operating Characteristic Curve was 0.797 (95%CI: 0.722-0.871). The SWAL-QOL questionnaire revealed significantly lower scores across all dimensions in patients with dysphagia ( < 0.05), particularly in swallowing function, eating duration, and food selection.

CONCLUSION

Postoperative dysphagia is prevalent after posterior skull base surgery and significantly impairs quality of life. Routine screening and proactive management of swallowing function are essential for improving clinical outcomes and enhancing swallowing-related quality of life.

摘要

引言

本研究旨在评估后颅底手术患者的吞咽功能现状和生活质量,确定吞咽困难的危险因素,并为早期干预提供依据。

方法

前瞻性纳入2023年6月至2024年6月期间接受后颅底手术的患者。数据收集包括人口统计学信息、疾病相关细节、吞咽功能评估以及吞咽生活质量(SWAL-QOL)评分。采用逻辑回归分析确定影响吞咽困难的危险因素,同时使用SWAL-QOL问卷调查后颅底手术患者的生活质量。

结果

143例患者中,约50%出现术后吞咽困难。逻辑回归分析确定呛咳史、手术时长和营养风险总分是吞咽困难的独立预测因素。受试者工作特征曲线下面积为0.797(95%CI:0.722 - 0.871)。SWAL-QOL问卷显示,吞咽困难患者在所有维度的得分均显著降低(<0.05),尤其是在吞咽功能、进食时长和食物选择方面。

结论

后颅底手术后,术后吞咽困难很常见,且显著损害生活质量。对吞咽功能进行常规筛查和积极管理对于改善临床结局和提高吞咽相关生活质量至关重要。

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