Polymer Synthesis and Functional Materials Research Unit, Department of Chemistry, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang, Chalongkrung Road, Ladkrabang, Bangkok 10520, Thailand.
Polymer Synthesis and Functional Materials Research Unit, Department of Chemistry, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang, Chalongkrung Road, Ladkrabang, Bangkok 10520, Thailand.
Carbohydr Polym. 2021 May 15;260:117836. doi: 10.1016/j.carbpol.2021.117836. Epub 2021 Feb 18.
pH-sensitive polymeric dyes were fabricated by grafting phenol red (PR) and rosolic acid (RA) onto chitosan (CS) by a facile method. Successful grafting was confirmed by H NMR, FT-IR, UV-vis, XRD, and elemental analysis. The polymeric dyes exhibited no cell toxicity. The colorimetric pH-sensing films were fabricated by blending the polymeric dyes with CS to establish their pH-dependent color properties. The film color changed in the pH range 4-10, which may indicate food spoilage or wound status. Covalently grafting of polymeric dyes in the films led to excellent color stability, leaching resistance, and reversibility. Hence, the synthesized polymeric dyes had potential as pH-indicative colorants for food and biomedical fields.
通过简便的方法将酚红（PR）和玫红酸（RA）接枝到壳聚糖（CS）上，制备了对 pH 值敏感的聚合物染料。通过 1H NMR、FT-IR、UV-vis、XRD 和元素分析确认了接枝的成功。聚合物染料没有细胞毒性。将聚合物染料与 CS 混合制备比色 pH 传感膜，以建立其对 pH 值的依赖颜色特性。该膜在 pH 值 4-10 的范围内颜色发生变化，这可能表明食物变质或伤口状况。在膜中接枝聚合物染料导致了优异的颜色稳定性、耐浸出性和可逆性。因此，合成的聚合物染料有望成为食品和生物医学领域的 pH 值指示剂显色剂。
