Li Fulong, Chen Chao, Chen Xiaohong
School of Materials & Chemistry, University of Shanghai for Science & Technology Shanghai 200093 China
Shanghai Engineering Technology Research Center for High-Performance Medical Device Materials Shanghai 200093 China.
RSC Adv. 2024 Oct 11;14(44):32267-32283. doi: 10.1039/d4ra00075g. eCollection 2024 Oct 9.
In recent years, biodegradable medical polymer materials (BMPMs) have stood out among many biomedical materials due to their unique advantages, such as high mechanical strength, good biocompatibility, strong corrosion resistance and excellent processability. In this review, we first provide a brief introduction of biodegradable medical materials from both natural and synthetic perspectives, and then systematically categorize BMPMs based on their applications in clinical medicine and highlight the great progress they have made in recent years. Additionally, we also point out several overlooked areas in the research of BMPMs, offering guidance for comprehensive future exploration of these materials. Finally, in view of the complex challenges faced by BMPMs today, their future directions are scientifically proposed. This work contributes to the ongoing efforts of BMPMs in the biomedical field and provides a steppingstone for developing more effective BMPM-based products for clinical applications.
近年来,可生物降解医用高分子材料(BMPMs)因其独特优势,如高机械强度、良好的生物相容性、强耐腐蚀性和优异的加工性能,在众多生物医学材料中脱颖而出。在本综述中,我们首先从天然和合成两个角度简要介绍可生物降解医用材料,然后根据其在临床医学中的应用对BMPMs进行系统分类,并突出它们近年来取得的重大进展。此外,我们还指出了BMPMs研究中几个被忽视的领域,为未来全面探索这些材料提供指导。最后,鉴于BMPMs目前面临的复杂挑战,科学地提出了它们的未来发展方向。这项工作有助于BMPMs在生物医学领域的持续努力,并为开发更有效的基于BMPM的临床应用产品提供了一块垫脚石。