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CAR T cells targeting CD13 controllably induce eradication of acute myeloid leukemia with a single domain antibody switch.

作者信息

He Xin, Feng Zijie, Ma Jian, Zhang Xuyao, Ling Sunbin, Cao Yan, Xing Bowen, Wu Yuan, Wang Lei, Katona Bryson W, June Carl H, Hua Xianxin

机构信息

Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.

Department of Cancer Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Leukemia. 2021 Nov;35(11):3309-3313. doi: 10.1038/s41375-021-01208-2. Epub 2021 Mar 12.

DOI:10.1038/s41375-021-01208-2
PMID:33712688
Abstract
摘要

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