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择期与紧急院内经导管主动脉瓣植入术。

Elective versus urgent in-hospital transcatheter aortic valve implantation.

机构信息

Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, UK.

Department of Cardiology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.

出版信息

Catheter Cardiovasc Interv. 2021 Jul 1;98(1):170-175. doi: 10.1002/ccd.29638. Epub 2021 Mar 13.

Abstract

BACKGROUND

Transcatheter aortic valve implantation (TAVI) is maturing as a treatment option and is now often undertaken during an unscheduled index hospital admission. The aim of this study was to look at procedural and mid-term outcomes of patients undergoing elective versus urgent in-hospital transcatheter aortic valve implantation.

METHODS

We identified a total of 1,157 patients who underwent TAVI between November 2007 and November 2019 at the Sussex Cardiac Centre in the UK. We compared the demographics, procedural outcomes, 30-day and 1-year mortality between elective and urgent patients. Emergency and salvage TAVI cases were excluded.

RESULTS

Of the 1,157 patients who underwent the procedure, 975 (84.3%) had elective while 182 (15.7%) had urgent TAVI. Predominant aortic stenosis was more frequent in elective patients (91.7% vs. 77.4%); p < .01), while predominant aortic regurgitation was seen more commonly in the urgent group (11.5% vs. 4.2%; p < .01). Implantation success was similar between the elective (99.1%) and urgent group (99.4%). In-hospital (1.65% vs. 1.3%: p .11), 30 day (3.5% vs. 3.3%: p .81) and 1 year (10.9% vs. 11%; p .81) mortality rates were similar in the elective and urgent groups, respectively.

CONCLUSIONS

In contemporary practice, urgent TAVI undertaken on the index admission can be performed at similar risk to elective outpatient TAVI.

摘要

背景

经导管主动脉瓣植入术(TAVI)作为一种治疗选择日趋成熟,目前常在非计划性索引住院期间进行。本研究旨在观察择期与紧急院内经导管主动脉瓣植入术患者的手术过程和中期结果。

方法

我们共确定了 1157 名于 2007 年 11 月至 2019 年 11 月期间在英国苏塞克斯心脏中心接受 TAVI 的患者。我们比较了择期和紧急患者的人口统计学、手术结果、30 天和 1 年死亡率。排除急诊和挽救性 TAVI 病例。

结果

在接受该手术的 1157 名患者中,975 名(84.3%)为择期患者,182 名(15.7%)为紧急 TAVI 患者。择期患者中主要为主动脉瓣狭窄更为常见(91.7% vs. 77.4%;p<0.01),而紧急组中主要为主动脉瓣反流更为常见(11.5% vs. 4.2%;p<0.01)。择期组(99.1%)与紧急组(99.4%)的植入成功率相似。院内(1.65% vs. 1.3%:p=0.11)、30 天(3.5% vs. 3.3%:p=0.81)和 1 年(10.9% vs. 11%:p=0.81)死亡率在择期和紧急组中分别相似。

结论

在当代实践中,索引入院时进行紧急 TAVI 可与择期门诊 TAVI 一样安全。

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