概念创新：4P医学与4P手术
Conceptual innovation: 4P Medicine and 4P surgery.
作者信息
Slim K, Selvy M, Veziant J
机构信息
Department of digestive surgery, CHU Clermont-Ferrand, place Lucie et Raymond-Aubrac, 63003 Clermont-Ferrand, France.
Department of digestive surgery, CHU Clermont-Ferrand, place Lucie et Raymond-Aubrac, 63003 Clermont-Ferrand, France.
出版信息
J Visc Surg. 2021 Jun;158(3S):S12-S17. doi: 10.1016/j.jviscsurg.2021.01.003. Epub 2021 Mar 11.
The aim of this article is to present the concept of "4P medicine" i.e., medicine that is Personalized, Preventive, Predictive, and Participatory. We will discuss the evolution from cure-focused traditional medicine toward personalized medicine based on genome analysis. This new approach is illustrated by several clinical examples such as prevention of cardiovascular diseases (primary and secondary), prophylactic cancer surgery, targeted therapies, targeted peri-operative care and patient participation in their care. Finally, it will discuss the impact of this development on the health system of the future and the ethical questions raised by this new approach.
本文旨在介绍“4P医学”的概念，即个性化、预防性、预测性和参与性医学。我们将讨论从以治愈为重点的传统医学向基于基因组分析的个性化医学的演变。这种新方法通过几个临床实例得到说明，如心血管疾病（一级和二级）的预防、预防性癌症手术、靶向治疗、靶向围手术期护理以及患者参与自身护理。最后，将讨论这一发展对未来卫生系统的影响以及这种新方法引发的伦理问题。
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