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同一患者同时患喉癌和肺癌:一项回顾性研究。

Laryngeal cancer and lung cancer in the same patient: a retrospective study.

作者信息

Heeringa A, de Vries N, Snow G B, Stam J

机构信息

Department of Pulmonary Diseases, Free University Hospital, Amsterdam.

出版信息

Eur J Surg Oncol. 1988 Jun;14(3):209-11.

PMID:3371472
Abstract

Fifty-four patients with laryngeal cancer and lung cancer were analyzed with regard to histology and localization of the lung cancer, the time interval between the detection of the two tumours and survival. It appeared that most lung tumours were squamous cell carcinomas, half of which were centrally localized and most occurred metachronously in the first 4 years after the laryngeal carcinoma. The survival rate was poor, due to the fact that the bronchial carcinoma usually was found beyond a curative stage. It appears that the present follow-up in laryngeal cancer patients--frequent ENT-examination, yearly chest X-ray examination--is often inadequate for early detection of lung cancer and curative treatment. It might be that by intensifying follow-up in laryngeal cancer patients by bronchoscopy, sputum cytology and more frequent chest X-ray examination, more bronchial carcinomas would be detected in a curative stage.

摘要

对54例喉癌合并肺癌患者的肺癌组织学类型、定位、两种肿瘤发现的时间间隔及生存情况进行了分析。结果显示,大多数肺部肿瘤为鳞状细胞癌,其中一半为中央型,且大多数在喉癌发生后的前4年异时发生。生存率较低,原因是支气管癌通常在可治愈阶段之后才被发现。目前对喉癌患者的随访——定期耳鼻喉科检查、每年胸部X光检查——似乎常常不足以早期发现肺癌并进行根治性治疗。通过支气管镜检查、痰细胞学检查以及更频繁的胸部X光检查加强对喉癌患者的随访,可能会在可治愈阶段发现更多支气管癌。

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