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与标准物理治疗相比,针对腰痛患者的预后筛查与靶向治疗相结合的管理方法:一项系统评价与荟萃分析。

Management approach combining prognostic screening and targeted treatment for patients with low back pain compared with standard physiotherapy: A systematic review & meta-analysis.

作者信息

Ogbeivor Collins, Elsabbagh Lina

机构信息

Rehabilitation Department, John Hopkins Aramco Healthcare, Dhahran, Kingdom of Saudi Arabia.

出版信息

Musculoskeletal Care. 2021 Dec;19(4):436-456. doi: 10.1002/msc.1541. Epub 2021 Mar 14.

DOI:10.1002/msc.1541
PMID:33715261
Abstract

BACKGROUND

Research evidence suggests that a stratified care management approach is better at improving clinical and economic outcomes for low back pain (LBP) patients compared with usual care in the short-term. However, it is uncertain if these health and economic benefits are sustainable in the longer term.

OBJECTIVE

To determine the effectiveness of stratified care compared with standard physiotherapy for LBP treatment.

METHODS

A comprehensive search was undertaken of seven electronic databases (CINAHL, MEDLINE, Pedro, EMBASE, PsycINFO, Cochrane Register for Controlled Trials and Web of Science with full text. No time limits were applied, but studies were limited to English language publications and those involving human participants. Two independent reviewers undertook study selection, data extraction and appraisal of study RESULTS: In total, 6,842 patients (18 years and above) were included in the 8 trials reviewed - 4 were randomised controlled trials (RCTs) and the other 4 were non-RCTs. The pooled analysis of 3 studies (n = 2,460) demonstrated a strong evidence in favour of stratified care over standard care at improving overall pain (WMD [random] 0.46 [95% CI 0.21, 0.71]; P < 0.0003), with overall effect (Z = 3.6) and (RMDQ) scores (WMD [random] 0.71 [95% CI 0.05, 1.37]; P < 0.03), with overall effect (Z = 2.11) at 3, 4- and 6-months follow-up periods.

CONCLUSION

This current review demonstrated that a stratified care approach provides substantial clinical, economic and health related cost benefits in the medium and high-risk subgroups compared with usual care. Further research is needed for longer-term benefits.

摘要

背景

研究证据表明,与常规护理相比,分层护理管理方法在短期内改善腰痛(LBP)患者的临床和经济结局方面效果更佳。然而,这些健康和经济效益在长期内是否可持续尚不确定。

目的

确定分层护理与标准物理治疗相比对LBP治疗的有效性。

方法

对七个电子数据库(CINAHL、MEDLINE、Pedro、EMBASE、PsycINFO、Cochrane对照试验注册库和科学网全文数据库)进行了全面检索。未设置时间限制,但研究限于英文出版物以及涉及人类参与者的研究。两名独立评审员进行研究选择、数据提取和研究结果评估。

结果

在纳入综述的8项试验中,共纳入了6842名18岁及以上的患者——4项为随机对照试验(RCT),另外4项为非RCT。对3项研究(n = 2460)的汇总分析显示,有强有力的证据支持分层护理在改善总体疼痛方面优于标准护理(加权均数差[随机效应]0.46[95%置信区间0.21, 0.71];P < 0.0003),在3个月、4个月和6个月的随访期内总体效应(Z = 3.6)以及罗兰-莫里斯残疾问卷(RMDQ)评分(加权均数差[随机效应]0.71[95%置信区间0.05, 1.37];P < 0.03),总体效应(Z = 2.11)。

结论

当前综述表明,与常规护理相比,分层护理方法在中高风险亚组中提供了显著的临床、经济和健康相关成本效益。需要进一步研究以确定长期效益。

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