Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Student Research Committee, Faculty of Public Health Branch, Iran University of Medical Sciences, Tehran Iran.
Crit Rev Food Sci Nutr. 2022;62(22):6005-6015. doi: 10.1080/10408398.2021.1895062. Epub 2021 Mar 10.
Dyslipidemia/hyperlipidemia is recognized among the risk factors for lifestyle related diseases. A healthy diet, rich in vegetable oils such as rice bran oil (RBO), may aid to improve serum lipid levels. Thus, the aim of this study was to assess the effects of rice bran oil (RBO) consumption on serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c) and triglyceride (TG) levels in adults. The following online databases were searched for manuscripts published until October 7 2020: PubMed/Medline, Scopus, Clarivate Analytics' Web of Science, Cochrane Central Register of Controlled Trials, and Google Scholar. The effect sizes were expressed as weighted mean difference (WMD) with 95% confidence intervals (CI). A total of 8 eligible trials with 14 effect sizes were included in this meta-analysis. Our analysis revealed that the consumption of RBO significantly decreased serum TC (WMD: -7.29 mg/dL, 95% CI: -11.32, -3.25, P = 0.000), LDL-c (WMD: -7.62 mg/dL, 95% CI: -11.10, -4.14, P = 0.000) and TG (WMD: -9.19 mg/dL, 95% CI: -17.99, -0.38, P = 0.041) levels. So, available evidence suggests that RBO consumption can significantly decrease serum TC, LDL-c and TG levels. Hence, it may play a role in reducing dyslipidemia/hyperlipidemia risk.
血脂异常/高脂血症是与生活方式相关疾病的危险因素之一。健康饮食，富含米糠油（RBO）等植物油，可能有助于改善血清脂质水平。因此，本研究旨在评估米糠油（RBO）摄入对成年人血清总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-c）、高密度脂蛋白胆固醇（HDL-c）和甘油三酯（TG）水平的影响。截至 2020 年 10 月 7 日，我们在以下在线数据库中搜索了已发表的文献：PubMed/Medline、Scopus、Clarivate Analytics 的 Web of Science、Cochrane 中央对照试验注册库和 Google Scholar。效应大小表示为加权均数差值（WMD）和 95%置信区间（CI）。这项荟萃分析共纳入了 8 项符合条件的试验，共 14 个效应量。我们的分析表明，RBO 的摄入显著降低了血清 TC（WMD：-7.29mg/dL，95%CI：-11.32，-3.25，P=0.000）、LDL-c（WMD：-7.62mg/dL，95%CI：-11.10，-4.14，P=0.000）和 TG（WMD：-9.19mg/dL，95%CI：-17.99，-0.38，P=0.041）水平。因此，现有证据表明，RBO 的摄入可以显著降低血清 TC、LDL-c 和 TG 水平。因此，它可能在降低血脂异常/高脂血症风险方面发挥作用。
