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多中心研究:血液透析患者肱动脉转位的疗效。

Multicentre Study on the Efficacy of Brachial Artery Transposition Among Haemodialysis Patients.

机构信息

Department of Nephrology, Shizuoka General Hospital, Shizuoka, Japan; Department of Nephrology, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan.

Department of Nephrology, Shizuoka General Hospital, Shizuoka, Japan; Department of Molecular and Clinical Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

出版信息

Eur J Vasc Endovasc Surg. 2021 Jun;61(6):998-1006. doi: 10.1016/j.ejvs.2021.01.038. Epub 2021 Mar 11.

Abstract

OBJECTIVE

Brachial artery transposition (BAT) is not a well known method for obtaining vascular access (VA) for maintenance haemodialysis. This study evaluated the outcomes of BAT.

METHODS

This multicentre retrospective cohort study included 233 consecutive patients who underwent BAT between January 2012 and December 2013. The indications were inadequate vessels for obtaining VA, severe heart failure, hand ischaemia, central vein stenosis/occlusion, or a history of catheter/graft infection. The transposed brachial artery was used only for arterial inflow and other routes were used for outflow.

RESULTS

BAT was successful in 227 patients, and adequate blood flow was achieved during dialysis sessions. The first successful cannulation was after a median of 18 days. BAT was performed using superficial veins as the return route in 127 patients and arteriovenous fistula (AVF) creation in 63 patients to prevent maturation failure. In 41 patients with central venous catheterisation, the transposed brachial artery was used for arterial inflow. The complications of BAT were impaired wound healing in 14 patients, including skin necrosis in two; large aneurysms in six, including a mycotic pseudo-aneurysm in one; arterial thrombosis in five; hand ischaemia in five; lymphorrhoea in four; and haematoma/bleeding in three. The transposed brachial artery was abandoned in four, three, three, and one case of arterial thrombosis/stenosis, haematoma/bleeding, skin necrosis, and large aneurysm, respectively. Access to the return routes failed in 48 cases because of vein damage caused by cannulation in 22, AVF thrombosis/stenosis in 14, catheter infection in six, and catheter occlusion in six. At two years, the primary patency rates of the transposed brachial artery and access circuit were 88% and 54%, respectively.

CONCLUSION

BAT is a safe and effective technique. The patency was high for the transposed brachial artery but adequate for the access circuit. BAT can be considered for patients with an unobtainable standard arteriovenous access.

摘要

目的

肱动脉转位(BAT)并非众所周知的维持性血液透析血管通路(VA)获取方法。本研究评估了 BAT 的结果。

方法

这是一项多中心回顾性队列研究,纳入了 2012 年 1 月至 2013 年 12 月期间接受 BAT 的 233 例连续患者。适应证为 VA 血管获取不足、严重心力衰竭、手部缺血、中心静脉狭窄/闭塞或导管/移植物感染史。转位肱动脉仅用于动脉入流,其他途径用于流出。

结果

BAT 在 227 例患者中成功,透析过程中获得足够的血流。第一次成功穿刺的中位时间为 18 天。127 例患者采用浅静脉作为回流途径,63 例患者采用动静脉瘘(AVF)创建以防止成熟失败。在 41 例中心静脉置管患者中,转位肱动脉用于动脉入流。BAT 的并发症包括 14 例伤口愈合受损,包括 2 例皮肤坏死;6 例大动脉瘤,包括 1 例真菌性假性动脉瘤;5 例动脉血栓形成;5 例手部缺血;4 例淋巴漏;3 例血肿/出血。由于动脉血栓形成/狭窄、血肿/出血、皮肤坏死和大动脉瘤,分别有 4 例、3 例、3 例和 1 例放弃转位肱动脉。由于 22 例穿刺导致静脉损伤、14 例 AVF 血栓形成/狭窄、6 例导管感染和 6 例导管闭塞,48 例无法进入回流途径。两年时,转位肱动脉和通路的主要通畅率分别为 88%和 54%。

结论

BAT 是一种安全有效的技术。转位肱动脉的通畅率高,但通路的通畅率足够。对于无法获得标准动静脉通路的患者,可以考虑 BAT。

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