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肱动脉移位与导管作为维持性血液透析的三级血管通路:一项单中心回顾性研究。

Brachial artery transposition versus catheters as tertiary vascular access for maintenance hemodialysis: a single-center retrospective study.

机构信息

Department of Nephrology, Shizuoka General Hospital, 4-27-1 Kitaando, Aoi-ku, Shizuoka, 420-8527, Japan.

Division of Clinical Biostatistics, Research Support Center, Shizuoka General Hospital, Shizuoka, 420-8527, Japan.

出版信息

Sci Rep. 2022 Jan 10;12(1):306. doi: 10.1038/s41598-021-03860-1.

Abstract

Some hemodialysis patients are not suitable for creation of an arteriovenous fistula (AVF) or arteriovenous graft (AVG). However, they can receive a tunneled cuffed central venous catheter (tcCVC), but this carries risks of infection and mortality. We aimed to evaluate the safety and effectiveness of brachial artery transposition (BAT) versus those of tcCVC. This retrospective study evaluated hemodialysis patients who underwent BAT or tcCVC placement because of severe heart failure, hand ischemia, central venous stenosis or occlusion, inadequate vessels for creating standard arteriovenous access, or limited life expectancy. The primary outcome was whole access circuit patency. Thirty-eight patients who underwent BAT and 25 who underwent tcCVC placement were included. One-year patency rates for the whole access circuit were 84.6% and 44.9% in the BAT and tcCVC groups, respectively. The BAT group was more likely to maintain patency (unadjusted hazard ratio: 0.17, 95% confidence interval: 0.05-0.60, p = 0.006). The two groups did not have significantly different overall survival (log-rank p = 0.146), although severe complications were less common in the BAT group (3% vs. 28%, p = 0.005). Relative to tcCVC placement, BAT is safe and effective with acceptable patency in hemodialysis patients not suitable for AVF or AVG creation.

摘要

一些血液透析患者不适合建立动静脉瘘(AVF)或动静脉移植物(AVG)。然而,他们可以接受带隧道的带袖套中央静脉导管(tcCVC),但这会带来感染和死亡的风险。我们旨在评估肱动脉转位(BAT)与 tcCVC 的安全性和有效性。这项回顾性研究评估了因严重心力衰竭、手部缺血、中心静脉狭窄或闭塞、用于建立标准动静脉通路的血管不足或预期寿命有限而接受 BAT 或 tcCVC 置管的血液透析患者。主要结局是整个通路的通畅率。38 名接受 BAT 治疗和 25 名接受 tcCVC 置管的患者纳入研究。BAT 和 tcCVC 组的 1 年通路通畅率分别为 84.6%和 44.9%。BAT 组更有可能保持通路通畅(未调整的危险比:0.17,95%置信区间:0.05-0.60,p=0.006)。两组的总体生存率没有显著差异(对数秩检验 p=0.146),尽管 BAT 组严重并发症较少(3%比 28%,p=0.005)。与 tcCVC 置管相比,对于不适合建立 AVF 或 AVG 的血液透析患者,BAT 安全有效,具有可接受的通畅率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/8748867/52edfc55f0d9/41598_2021_3860_Fig1_HTML.jpg

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