Laschinski G, Spielmann H
Max-von-Pettenkofer-Institut des Bundesgesundheitsamtes.
Geburtshilfe Frauenheilkd. 1988 Mar;48(3):196-7. doi: 10.1055/s-2008-1035724.
During pregnancy vitamin A supplementation cannot generally be recommended, since an average diet contains a sufficient amount (7500 IE/day) of vitamin A, since a typical malformation pattern has been observed after excessive doses of vitamin A during human pregnancy, and since some vitamin A derivatives are embryotoxic and teratogenic both in animals and humans. Particular reference is given to the recommendations of the American Teratology Society for the use of vitamin A during pregnancy.
孕期一般不建议补充维生素A,因为普通饮食中维生素A含量充足(7500国际单位/天),因为人类孕期过量摄入维生素A后已观察到典型的畸形模式,还因为一些维生素A衍生物在动物和人类中均具有胚胎毒性和致畸性。特别提及美国致畸学会关于孕期使用维生素A的建议。