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Opioid Prescribing by Specialty and Volume in the U.S.美国按专业和处方量统计的阿片类药物处方情况
Am J Prev Med. 2018 Nov;55(5):e153-e155. doi: 10.1016/j.amepre.2018.06.008. Epub 2018 Sep 12.
2
Risk Reduction Compared with Access to Care: Quantifying the Trade-Off of Enforcing a Body Mass Index Eligibility Criterion for Joint Replacement.与获得医疗服务相比,风险降低:量化实施关节置换 BMI 资格标准的权衡取舍。
J Bone Joint Surg Am. 2018 Apr 4;100(7):539-545. doi: 10.2106/JBJS.17.00120.
3
Excess Opioid Medication and Variation in Prescribing Patterns Following Common Orthopaedic Procedures.术后常见骨科手术中阿片类药物的过量使用和处方模式的变化。
J Bone Joint Surg Am. 2018 Feb 7;100(3):180-188. doi: 10.2106/JBJS.17.00672.
4
Application of Tranexamic Acid in Total Knee Arthroplasty - Prospective Randomized Trial.氨甲环酸在全膝关节置换术中的应用——前瞻性随机试验
Open Orthop J. 2017 Aug 29;11:1049-1057. doi: 10.2174/1874325001711011049. eCollection 2017.
5
Risk for Prolonged Opioid Use Following Total Knee Arthroplasty in Veterans.退伍军人全膝关节置换术后长期阿片类药物使用的风险。
J Arthroplasty. 2018 Jan;33(1):119-123. doi: 10.1016/j.arth.2017.08.022. Epub 2017 Aug 24.
6
Narcotic Use and Total Knee Arthroplasty.阿片类药物使用与全膝关节置换术。
J Arthroplasty. 2018 Jan;33(1):113-118. doi: 10.1016/j.arth.2017.08.006. Epub 2017 Aug 17.
7
Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status.全关节置换术后根据肥胖状况的功能改善和疼痛缓解
J Bone Joint Surg Am. 2017 Jul 19;99(14):1183-1189. doi: 10.2106/JBJS.16.00960.
8
Intra-articular Application is More Effective Than Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.关节内应用氨甲环酸比静脉应用氨甲环酸在全膝关节置换术中更有效:一项前瞻性随机对照试验。
J Arthroplasty. 2017 Nov;32(11):3385-3389. doi: 10.1016/j.arth.2017.06.024. Epub 2017 Jun 21.
9
Impact of Preoperative Opioid Use on Total Knee Arthroplasty Outcomes.术前使用阿片类药物对全膝关节置换术结果的影响。
J Bone Joint Surg Am. 2017 May 17;99(10):803-808. doi: 10.2106/JBJS.16.01200.
10
Pain Management Modalities after Total Knee Arthroplasty: A Network Meta-analysis of 170 Randomized Controlled Trials.全膝关节置换术后的疼痛管理方式:170 项随机对照试验的网络荟萃分析。
Anesthesiology. 2017 May;126(5):923-937. doi: 10.1097/ALN.0000000000001607.

关节手术后减少阿片类药物使用:初次全膝关节置换术后减少术后阿片类药物使用的方案

Minimizing Opioids After Joint Operation: Protocol to Decrease Postoperative Opioid Use After Primary Total Knee Arthroplasty.

作者信息

Woelber Erik, Wurster Lindsey, Brandt Sarah, Mecum Patricia, Gundle Kenneth, Anissian Lucas

机构信息

and are Physician Assistants, is a Family Nurse Practitioner, and are Attending Orthopedic Surgeons, all at US Department of Veterans Affairs Portland Health Care System in Oregon. is an Orthopedic Surgery Resident, and Kenneth Gundle is an Attending Physician, both in the Orthopedic Department at Oregon Health and Sciences University in Portland.

出版信息

Fed Pract. 2021 Feb;38(2):e1-e7. doi: 10.12788/fp.0092.

DOI:10.12788/fp.0092
PMID:33716488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7953855/
Abstract

BACKGROUND

For decades, opioids have been the mainstay in pain management after total joint arthroplasty despite evidence that their use should be curtailed. To limit unnecessary prescribing of opioids, the US Department of Veterans Affairs (VA) Portland Health Care System Total Joints Service implemented the Minimizing Opioids After Joint Operation (MOJO) postoperative pain protocol in 2018 to reduce opioid use following total knee arthroplasty (TKA). This protocol included reductions of inpatient and outpatient opioid prescribing, preoperative optimization, use of perioperative nerve blocks, and surgery without a tourniquet.

METHODS

We performed a retrospective chart review that compared the first 20 consecutive patients undergoing TKA using the MOJO protocol with the last 20 patients using the prior routine. Outcomes included total inpatient opioid use, daily opioid use, emergency department (ED) visits or readmissions within 90 days, phone calls for pain or medication refills, length of stay (LOS), and pain during inpatient hospital stay.

RESULTS

There were significant differences between the pre-MOJO and the MOJO groups with regard to daily inpatient morphine equivalent dose (MED) (82 mg vs 31 mg, < .01) and total inpatient MEDs (306 mg vs 33 mg, < .01). There was less self-reported pain on postoperative day 1 in the MOJO group (5.5 vs 4.1, = .01), decreased LOS (4.4 days vs 1.1 days, < .01), fewer total ED visits (6 vs 2, < .07), and fewer discharges to skilled nursing facilities (12 vs 0, < .01).

CONCLUSIONS

The MOJO protocol reduced postoperative opioid use after TKA in the VA setting without compromising pain control or increasing ED visits. The framework and routines described are potentially applicable to other institutions and surgical specialties.

摘要

背景

几十年来,尽管有证据表明应减少阿片类药物的使用,但在全关节置换术后的疼痛管理中,阿片类药物一直是主要用药。为限制阿片类药物的不必要处方,美国退伍军人事务部(VA)波特兰医疗保健系统全关节服务部于2018年实施了关节手术后减少阿片类药物使用(MOJO)的术后疼痛方案,以减少全膝关节置换术(TKA)后的阿片类药物使用。该方案包括减少住院和门诊阿片类药物处方、术前优化、围手术期神经阻滞的使用以及不使用止血带进行手术。

方法

我们进行了一项回顾性病历审查,将连续接受TKA手术的前20例使用MOJO方案的患者与最后20例使用先前常规方案的患者进行了比较。结果包括住院期间阿片类药物的总使用量、每日阿片类药物使用量、90天内急诊室(ED)就诊或再入院情况、因疼痛或药物补充而拨打的电话、住院时间(LOS)以及住院期间的疼痛情况。

结果

在每日住院吗啡当量剂量(MED)方面,MOJO方案前组与MOJO方案组之间存在显著差异(82毫克对31毫克,<0.01),住院期间MED总量也有差异(306毫克对33毫克,<0.01)。MOJO方案组术后第1天的自我报告疼痛较轻(5.5对4.1,=0.01),住院时间缩短(4.4天对1.1天,<0.01),急诊室就诊总数减少(6次对2次,<0.07),转至专业护理机构的出院人数减少(12人对0人,<0.01)。

结论

在VA环境中,MOJO方案减少了TKA术后的阿片类药物使用,且不影响疼痛控制或增加急诊室就诊次数。所描述的框架和常规方法可能适用于其他机构和外科专科。