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扁桃体切除术后发现的一例偶然的潜伏性成人血友病病例。

An incidental latent adult hemophilia case found after a tonsillectomy.

作者信息

Saikawa Yuichiro, Tsunoda Atsunobu, Sata Naoko, Anzai Takashi

机构信息

Department of Otolaryngology, Juntendo University Nerima Hospital, Tokyo, Japan.

出版信息

SAGE Open Med Case Rep. 2021 Feb 27;9:2050313X20988410. doi: 10.1177/2050313X20988410. eCollection 2021.

Abstract

Severe bleeding after a tonsillectomy may cause airway obstruction and be life-threatening. We report post-tonsillectomy bleeding in a 32-year-old patient with hemophilia A, who had not been aware of his disease for more than 30 years. He underwent tonsillectomy for recurrent tonsillitis. He denied episodes of bleeding tendency. The preoperative workup was normal, including platelet count, prothrombin time, and activated partial thromboplastin time. The surgery itself was uneventful, but severe bleeding from the inferior pole of the tonsillar bed developed 7 days after surgery. Emergency hemostasis was performed under general anesthesia in the operating room. The patient then remembered several episodes of bleeding tendency. Coagulation tests revealed a mild lack of coagulation factor VIII to 35%, and a diagnosis of hemophilia A was made. Hemophilia might only be found after surgery and can cause life-threatening complications. However, latent hemophilia detected after a tonsillectomy in a 32-year-old adult is very rare. A careful history of bleeding tendency is important to achieve a diagnosis of coagulopathy, perform a safer surgery, and prevent postoperative complications.

摘要

扁桃体切除术后严重出血可能导致气道阻塞并危及生命。我们报告了一名32岁的甲型血友病患者扁桃体切除术后出血的病例,该患者30多年来一直未意识到自己患有此病。他因复发性扁桃体炎接受了扁桃体切除术。他否认有出血倾向发作史。术前检查正常,包括血小板计数、凝血酶原时间和活化部分凝血活酶时间。手术过程顺利,但术后7天扁桃体床下极出现严重出血。在手术室全身麻醉下进行了紧急止血。随后患者回忆起几次出血倾向发作史。凝血检查显示凝血因子VIII轻度缺乏至35%,从而确诊为甲型血友病。血友病可能仅在手术后才被发现,并可导致危及生命的并发症。然而,在一名32岁成年人扁桃体切除术后发现潜在血友病的情况非常罕见。仔细询问出血倾向病史对于诊断凝血病、进行更安全的手术以及预防术后并发症很重要。

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An incidental latent adult hemophilia case found after a tonsillectomy.扁桃体切除术后发现的一例偶然的潜伏性成人血友病病例。
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