Zondervan H A, Oosting J, Smorenberg-Schoorl M E, Treffers P E
Department of Obstetrics and Gynecology, University of Amsterdam, The Netherlands.
Gynecol Obstet Invest. 1988;25(2):83-8. doi: 10.1159/000293751.
Hemoconcentration is prominent in preeclampsia. Concomitant changes in the flow properties of maternal blood, i.e. in whole blood viscosity (WBV), might be related to the occurrence of fetal or maternal complications. To test this hypothesis, WBV was estimated in 228 pregnancies. Patients were assigned to one of four groups according to maximum diastolic blood pressure. Significantly higher WBV values were found in the more hypertensive groups throughout pregnancy. WBV data, obtained between 26 and 36 weeks of amenorrhea, contributed significantly, independently of hypertension, to the prediction of fetal outcome. With regard to maternal complications, no significant contribution of WBV data could be established independently of blood pressure. The results support the hypothesis that WBV is a determining factor in the efficacy of placental perfusion.
血液浓缩在子痫前期较为突出。母体血液流动特性的相应变化，即全血粘度（WBV）的变化，可能与胎儿或母体并发症的发生有关。为验证这一假设，对228例妊娠孕妇的全血粘度进行了评估。根据最大舒张压将患者分为四组。在整个孕期，高血压程度较高的组全血粘度值显著更高。在闭经26至36周期间获得的全血粘度数据，独立于高血压因素，对胎儿结局的预测有显著贡献。关于母体并发症，全血粘度数据独立于血压因素未显示出显著贡献。这些结果支持了全血粘度是胎盘灌注效能决定因素的假设。
