Frey M, Girsch W, Gruber I, Happak W, Gruber H
Abteilung für Plastische und Wiederherstellende Chirurgie, Universität Wien.
Handchir Mikrochir Plast Chir. 1988 Mar;20(2):76-82.
A survey of publications dealing with vascularized nerve grafts is given. The advantages and disadvantages are discussed by analyzing the published data. Until now the superiority of vascularized nerve grafts has not been proven by the published experimental and clinical results. This fact was underlined by the results of our own experimental investigations: In conventional nerve grafts performed on sheep it was shown that the functional results of reinnervation cannot be correlated to the degree of vascularization of the nerve graft or to number and morphology of the regenerated axons. Therefore, the indications for the clinical application of the vascularized nerve graft must be limited to the following conditions: Poorly vascularized recipient bed, thick nerve graft, unsuccessful previous conventional nerve grafting, and the necessity of vascular reconstruction at the same time.
本文对有关带血管神经移植的文献进行了综述。通过分析已发表的数据讨论了其优缺点。迄今为止,已发表的实验和临床结果尚未证实带血管神经移植的优越性。我们自己的实验研究结果也强调了这一事实:在对绵羊进行的传统神经移植中发现,神经再支配的功能结果与神经移植的血管化程度、再生轴突的数量和形态无关。因此,带血管神经移植临床应用的适应证必须限于以下情况:受区血管化不良、神经移植体粗大、先前传统神经移植失败以及同时需要进行血管重建。