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新冠疫情期间甲基苯丙胺所致肺损伤1例罕见病例

A Rare Case of Methamphetamine-Induced Lung Injury During the Ongoing COVID-19 Pandemic.

作者信息

Javed Anam, Nasrullah Adeel, Malik Khalid

机构信息

Internal Medicine, Allegheny Health Network, Pittsburgh, USA.

Pulmonary and Critical Care Medicine, Allegheny Health Network, Pittsburgh, USA.

出版信息

Cureus. 2021 Feb 8;13(2):e13215. doi: 10.7759/cureus.13215.

Abstract

Methamphetamine-induced lung injury is a very rare entity and is poorly understood due to the paucity of available literature. It can present with respiratory failure, often requiring immediate ventilatory support and conservative management. Secondary bacterial infection can result from smoking contaminated crystalline methamphetamine. Although there is growing evidence for the use of steroids in acute respiratory distress syndrome (ARDS), the literature is limited regarding cases of non-cardiogenic pulmonary edema due to meth use. We present a case of ARDS due to methamphetamine use, which dramatically resolved with ventilatory support. A low threshold to investigate drug-induced lung injury in suspicious cases can limit unnecessary utilization of resources during the ongoing coronavirus disease 2019 (COVID-19) pandemic.

摘要

甲基苯丙胺所致肺损伤是一种非常罕见的病症,由于现有文献匮乏,人们对其了解甚少。它可表现为呼吸衰竭,常常需要立即进行通气支持和保守治疗。吸食受污染的结晶甲基苯丙胺可能导致继发性细菌感染。尽管越来越多的证据表明在急性呼吸窘迫综合征(ARDS)中可使用类固醇,但关于甲基苯丙胺所致非心源性肺水肿病例的文献有限。我们报告一例因使用甲基苯丙胺导致的ARDS病例,该病例在通气支持下显著缓解。在2019冠状病毒病(COVID-19)大流行期间,对于可疑病例,保持较低的药物性肺损伤调查阈值可减少资源的不必要利用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b039/7944429/26afcd96260e/cureus-0013-00000013215-i01.jpg

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