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哈里斯血小板综合征患者行前列腺经尿道切除术时的区域麻醉——临床难题还是确定无疑?

Regional Anaesthesia in Harris Platelet Syndrome for Transurethral Resection of Prostate-A Clinical Conundrum or Certitude?

作者信息

Neethirajan Soma Ganesh Raja, Ramesh Aishwarya, Parameswari Aruna

机构信息

Department of Anaesthesia and Pain Medicine, Sri Ramachandra Medical College and Research Institute, Chennai, India.

出版信息

Turk J Anaesthesiol Reanim. 2021 Feb;49(1):67-69. doi: 10.5152/TJAR.2020.90008. Epub 2020 May 5.

DOI:10.5152/TJAR.2020.90008
PMID:33718909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7932712/
Abstract

Routine use of the autoanalyzer has helped uncover the increasing incidence of thrombocytopenia. Disorders associated with macrothrombocytes with thrombocytopenia necessitate a preoperative evaluation to assess the bleeding tendencies and the need for transfusion of blood products. Harris platelet syndrome is one such disorder where macrothrombocytes with thrombocytopenia are associated with no congenital abnormalities and low risk of bleeding intraoperatively. There are cases where Harris platelet syndrome has been treated with steroids or splenectomy, which is unwarranted. We report successful management of a patient with Harris platelet syndrome who underwent transurethral resection of the prostate under spinal anaesthesia with no complications.

摘要

自动分析仪的常规使用有助于发现血小板减少症发病率的上升。伴有血小板减少症的大血小板相关疾病需要进行术前评估,以评估出血倾向和输血制品的需求。哈里斯血小板综合征就是这样一种疾病,其中伴有血小板减少症的大血小板与无先天性异常及术中低出血风险相关。有一些哈里斯血小板综合征病例用类固醇或脾切除术进行了治疗,这是不必要的。我们报告了一名哈里斯血小板综合征患者在脊髓麻醉下接受经尿道前列腺切除术并成功管理且无并发症的病例。

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Regional Anaesthesia in Harris Platelet Syndrome for Transurethral Resection of Prostate-A Clinical Conundrum or Certitude?哈里斯血小板综合征患者行前列腺经尿道切除术时的区域麻醉——临床难题还是确定无疑?
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本文引用的文献

1
Macrothrombocytopenia in north India: role of automated platelet data in the detection of an under diagnosed entity.印度北部的巨血小板减少症:自动血小板数据在检测未被充分诊断的病症中的作用
Indian J Hematol Blood Transfus. 2015 Mar;31(1):61-7. doi: 10.1007/s12288-014-0367-3. Epub 2014 Apr 2.
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Differential proteomics study of platelets in asymptomatic constitutional macrothrombocytopenia: altered levels of cytoskeletal proteins.无症状性体质性巨血小板减少症血小板的差异蛋白质组学研究:细胞骨架蛋白水平的改变
Eur J Haematol. 2015 Jan;94(1):43-50. doi: 10.1111/ejh.12398. Epub 2014 Jul 16.
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Platelet and red blood cell indices in Harris platelet syndrome.哈里斯血小板综合征中的血小板和红细胞指数。
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Identification of inherited macrothrombocytopenias based on mean platelet volume among patients diagnosed with idiopathic thrombocytopenia.基于平均血小板体积在特发性血小板减少症诊断患者中识别遗传性大血小板减少症。
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Harris syndrome - a geographic perspective.哈里斯综合征——地域视角
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Asymptomatic constitutional macrothrombocytopenia among West Bengal blood donors.西孟加拉邦献血者中的无症状体质性巨血小板减少症
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Inherited giant platelet disorders. Classification and literature review.遗传性巨大血小板疾病。分类及文献综述。
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