[用于组织再生研究与应用的血小板衍生物标准化管理]
[Standardized management of platelet derivatives for tissue regeneration research and applications].
作者信息
Xie Xingqin, Zhang Yi, Zhao Xinxin, Liu Tongxin, Sun Liping
机构信息
National and Local Joint Stem Cell Research and Engineering Center for Aging Diseases, Harbin Heilongjiang, 150028, P.R.China;R&D Center, Tian Qing Stem Cell Co., Ltd., Harbin Heilongjiang, 150028, P.R.China.
R&D Center, Tian Qing Stem Cell Co., Ltd., Harbin Heilongjiang, 150028, P.R.China.
出版信息
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2021 Mar 15;35(3):392-398. doi: 10.7507/1002-1892.202011023.
OBJECTIVE
To summary the standardized management in research and applications of platelet derivatives for tissue regeneration.
METHODS
The related literature about bottlenecks and standardized management of platelet derivatives in recent years was reviewed and analyzed.
RESULTS
Although the platelet derivatives are increasingly used to accelerate the regenerative processes of injured joint, skin, nerve, ligament/tendon, and alveolar bone, ., the large variation in preparation methods, diverse nomenclature, incomplete reporting system, and lack of quantitative and standardized management of the preparation process have caused uncertainty and incomparability of research and application results. In recent years, there has been a trend towards standardized research and management of platelet derivatives.
CONCLUSION
The implementation of standardized research and quality management will contribute to promote the research and application of platelet derivatives in the field of tissue regeneration.
目的
总结血小板衍生物在组织再生研究与应用中的标准化管理。
方法
回顾并分析近年来有关血小板衍生物瓶颈问题及标准化管理的相关文献。
结果
尽管血小板衍生物越来越多地用于加速受损关节、皮肤、神经、韧带/肌腱和牙槽骨的再生过程，……，但制备方法差异大、命名多样、报告系统不完整以及制备过程缺乏定量和标准化管理，导致研究和应用结果存在不确定性和不可比性。近年来，血小板衍生物的研究和管理有走向标准化的趋势。
结论
实施标准化研究和质量管理将有助于推动血小板衍生物在组织再生领域的研究与应用。
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