Wikman Agneta, Larsson Stella, Storry Jill, Schött Ulf, Sato Folatre José-Gabriel
docent, överläkare, Klinisk immunologi och transfusionsmedicin, Karolinska universitetssjukhuset, Stockholm.
med dr, överläkare, Klinisk immunologi och transfusionsmedicin, Karolinska universitetssjukhuset, Stockholm.
Lakartidningen. 2021 Mar 15;118:20150.
Sweden does not have a national blood authority and guidelines for blood transfusions are lacking, leading to varying routines of production and usage of blood in the different regions. The minimum quality requirements are defined in EU Directive 2002/98/EG and in the Swedish SOSFS 2009:28. The standard blood components are red blood cells, plasma and platelets, while special components such as irradiated, washed, frozen-thawed or antigen-matched products are prescribed on certain clinical indications. Thresholds for transfusion of red blood cells and platelets are discussed as well as indications for plasma transfusions. Further, there is evidence that early, balanced blood transfusions in massive bleeding reduce mortality, which has led to requests for blood products in prehospital settings.
瑞典没有国家血液管理机构,也缺乏输血指南,这导致不同地区血液生产和使用的常规做法各不相同。最低质量要求在欧盟指令2002/98/EG和瑞典SOSFS 2009:28中有所规定。标准血液成分包括红细胞、血浆和血小板,而诸如辐照、洗涤、冻融或抗原匹配产品等特殊成分则根据特定临床指征开具。还讨论了红细胞和血小板输血的阈值以及血浆输血的指征。此外,有证据表明,在大出血时早期、均衡输血可降低死亡率,这导致了院前环境中对血液制品的需求。