奥卡西替尼治疗猫寻常型天疱疮病例的疗效观察。

Beneficial effect of oclacitinib in a case of feline pemphigus foliaceus.

机构信息

Servicio Dermatología Hospital Veterinario Canis, Agnés de Pacs 12, Palma de Mallorca, 07010, Spain.

Citopat Veterinaria, Provença 392, Barcelona, 08025, Spain.

出版信息

Vet Dermatol. 2021 Jun;32(3):299-301. doi: 10.1111/vde.12949. Epub 2021 Mar 15.

DOI:10.1111/vde.12949

PMID:33720467

Abstract

Pemphigus foliaceous (PF) is a pustular, immune-mediated skin disease characterised by acantholytic cells and commonly treated with high doses of glucocorticoids. This report describes one case of feline PF successfully controlled using oral oclacitinib, suggesting a possible therapeutic alternative to glucocorticoids in some cases.

摘要

落叶型天疱疮（PF）是一种脓疱性、免疫介导性皮肤疾病，其特征为棘层松解细胞，通常采用大剂量糖皮质激素治疗。本报告描述了一例成功使用口服奥卡西替尼治疗的猫 PF 病例，这提示在某些情况下奥卡西替尼可能是糖皮质激素的一种替代治疗选择。