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肉瘤合并 COVID-19 感染患者的结局:单中心队列分析。

Outcomes of Patients with Sarcoma and COVID-19 Infection: A Single Institution Cohort Analysis.

机构信息

Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.

Clinical Research Division, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, Washington, USA.

出版信息

Cancer Invest. 2021 Apr;39(4):315-320. doi: 10.1080/07357907.2021.1903914. Epub 2021 Mar 26.

DOI:10.1080/07357907.2021.1903914
PMID:33720792
Abstract

Outcomes for patients (pts) with sarcoma and COVID-19 are unknown. This is a single institution retrospective study of adults with sarcoma and COVID-19. Ten pts [median age 60 (range 24-69)] were identified. Five were hospitalized; two died from COVID-19 complications; another died from sarcoma. Time between last systemic treatment dose and COVID-19 diagnosis was 6-41 days in pts who died. 5 underwent prior radiation (RT); time between RT and COVID-19 diagnosis was 20-62 days for pts who died. All three pts with WBC differential data (two died) were lymphopenic. Efforts to capture outcomes for a larger cohort are urgently needed.

摘要

患有肉瘤和 COVID-19 的患者的预后情况尚不清楚。这是一项针对患有肉瘤和 COVID-19 的成年人的单机构回顾性研究。共确定了 10 名患者[中位年龄 60 岁(范围 24-69 岁)]。其中 5 名患者住院治疗;2 名患者因 COVID-19 并发症死亡;另一名患者因肉瘤死亡。死亡患者最后一次全身治疗剂量与 COVID-19 诊断之间的时间间隔为 6-41 天。5 名患者接受了放射治疗(RT);死亡患者 RT 与 COVID-19 诊断之间的时间间隔为 20-62 天。所有 3 名具有白细胞分类数据的患者(2 人死亡)均为淋巴细胞减少症。迫切需要努力获取更大队列的结果数据。

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